This Special Communication uses a systematic literature review to update previous dollar estimates of waste in the US health care system attributable to failure of care delivery and coordination, low-value care, price inflation, fraud, and administrative complexity. | Continue reading
This survey study analyzes the prevalence and patterns of marijuana use among adults with and without medical conditions using data from the 2016 and 2017 Behavioral Risk Factor Surveillance System surveys. | Continue reading
This systematic review and meta-analysis examines the association between birth by cesarean delivery and risk of neurodevelopmental and psychiatric disorders in the offspring compared with birth by vaginal delivery. | Continue reading
This cross-sectional study examines time trends and sex differences in the suicide mortality rate among US youths adjusted for birth cohort and age. | Continue reading
This cohort study examines incidence of intellectual disability, attention-deficit/hyperactivity disorder, depression, and health outcomes associated with relative age of children vs classmates. | Continue reading
This survey study assesses the practices related to courtesy authorship in surgical journals and academia. | Continue reading
This randomized trial compares the effects of 400 vs 4000 vs 10 000 IU of vitamin D on total volumetric bone mineral density and bone strength of the radius and tibia. | Continue reading
This cohort study examines whether soft drink consumption is associated with all-cause and cause-specific mortality in a large cohort of European adults. | Continue reading
This analysis of prospective data from the Avon Longitudinal Study of Parents and Children investigates the association between paternal depression in the postnatal period and offspring depression at age 18 years and identifies potential mediating and moderating factors for this … | Continue reading
This meta-analysis compares cognitive performance of individuals with major depressive disorder with that of their first-degree relatives. | Continue reading
This cohort study of 16 741 older women from the Women’s Health Study examines associations of number of steps per day and stepping intensity with all-cause mortality. | Continue reading
This study examines the association between fluoride exposure during pregnancy and IQ scores in a prospective birth cohort. | Continue reading
This study examines the association between fluoride exposure during pregnancy and IQ scores in a prospective birth cohort. | Continue reading
This cohort study of healthy individuals in England who underwent repeated bone density scans from ages 10 to 25 years describes the association between the timing of puberty and bone mineral density. | Continue reading
This Viewpoint uses Dinerstein v Google, a class action complaint in Illinois alleging that an academic medical center violated patient privacy by giving timestamped electronic health record (EHR) data to Google for development of their novel EHR system, to review the ways privac … | Continue reading
In 2019, the US Food and Drug Administration approved esketamine for treatment of major depressive disorder unresponsive to other therapies when given in a health care facility because of its transient effects on vital signs and feelings of dissociation it can produce acutely. Th … | Continue reading
This population-based cohort study uses national registry data from 5 countries to investigate additive genetic, maternal, and environmental effects on autism spectrum disorder diagnosis. | Continue reading
This Viewpoint reviews the discrepancy in prices paid for hospital services by commercial insurers vs Medicare and Medicaid, and calls for greater hospital accountability, cost transparency, and data to guide pricing so that the cost of services are benchmarked to the value they … | Continue reading
Between 2016 and 2018, US government personnel stationed in Havana, Cuba, reported exposure to unusual auditory and sensory phenomena followed by neurological signs and symptoms characterized clinically as cognitive, vestibular, and oculomotor dysfunction with sleep impairment an … | Continue reading
This population-based cohort study uses national registry data from 5 countries to investigate additive genetic, maternal, and environmental effects on autism spectrum disorder diagnosis. | Continue reading
This nested case-control study including 58 769 patients diagnosed with dementia and 225 574 matched controls 55 years or older evaluates whether, and to what extent, anticholinergic drug exposure was associated with dementia risk. | Continue reading
This study uses Centers for Disease Control and Prevention (CDC) data to characterize trends in suicide rates among adolescents and young adults aged 15 to 24 years in the United States and to determine if the increase in suicide rates observed in years 2000-2016 is continuing. | Continue reading
This meta-analysis of 21 randomized clinical trials examines the role of vitamin D supplementation in reducing cardiovascular events and all-cause mortality. | Continue reading
This study uses Centers for Disease Control and Prevention (CDC) data to characterize trends in suicide rates among adolescents and young adults aged 15 to 24 years in the United States and to determine if the increase in suicide rates observed in years 2000-2016 is continuing. | Continue reading
In this Viewpoint, Woolhandler and Himmelstein review the potential benefits of single-payer health care reform, including savings on administrative costs and lower drug prices, and argue against partial solutions that might expand coverage without reducing costs and waste. | Continue reading
This Medical News story discusses a recent study that suggests sleeping late on the weekend cannot mitigate the metabolic dysregulation associated with recurrent insufficient sleep during the week. | Continue reading
This cohort study assesses the appropriateness of antibiotic prophylaxis prescriptions for infection prophylaxis before dental procedures using Truven, a US national integrated health claims database. | Continue reading
This cohort study of 16 741 older women from the Women’s Health Study examines associations of number of steps per day and stepping intensity with all-cause mortality. | Continue reading
This study reports the seeming disparity in access to buprenorphine prescriptions among racial/ethnic minorities and individuals with lower income. | Continue reading
This systematic review and meta-analysis assesses the risk of intracranial hemorrhage associated with low-dose aspirin among individuals without symptomatic cardiovascular disease. | Continue reading
In this Viewpoint, Victor Fuchs reviews the evolution of the US employer-based health insurance toward a system favoring higher-income individuals, and proposes reforms in health care financing and in accessibility of lower-cost care as a way to make the system more fair and effi … | Continue reading
This randomized clinical trial recruited healthy volunteers to assess whether the active ingredients of commercially available sunscreen products (avobenzone, oxybenzone, octocrylene, and ecamsule) are absorbed into systemic circulation under maximal use conditions. | Continue reading
In this Viewpoint, authors from the Vatican, academic medicine, and climate sciences highlight areas of consensus about climate change in their respective health, science, and faith communities and call for global collaboration to mitigate its effects, reduce health disparities, … | Continue reading
In the wake of the suicides of 2 students who survived the 2018 Parkland, Florida, mass shooting, this Viewpoint reviews evidence about the long-term adverse psychological effects of mass shootings on survivors and their families and communities, and proposes that changes in ment … | Continue reading
This network meta-analysis examines and compares different methods of delivering cognitive behavior therapy to adult patients with depression. | Continue reading
This cluster randomized clinical trial evaluates the effects of a workplace wellness program comprising nutrition, physical activity, and stress reduction modules on self-reported lifestyle outcomes (exercise, diet, smoking, alcohol use), clinical measures (eg, cholesterol, blood … | Continue reading
This survey study uses difference-in-difference analysis of national longitudinal survey data to examine the association between nationwide public disclosure of industry payments and Americans’ trust in their physicians and in the medical profession. | Continue reading
This pooled cohort study reports that consumption of an additional 300 mg of dietary cholesterol per day or an additional half egg per day is significantly associated with higher risk of incident cardiovascular disease (CVD) events and all-cause mortality. | Continue reading
This cohort study evaluates whether prior use of electronic cigarettes (e-cigarettes) and other tobacco products by US youths is associated with subsequent initation of cigarette smoking. | Continue reading
This population-based cohort study examines comorbidity within mental disorders, provides temporally ordered age- and sex-specific pairwise estimates between the major groups of mental disorders, and develops an interactive website to visualize all results and guide future resear … | Continue reading
This meta-analysis quantifies the rates of suicide after discharge from psychiatric facilities and examines what moderates those rates. | Continue reading
This cohort study evaluates the association between the introduction of Medicaid Healthy Behavior Incentive Programs and the rates of smoking cessation, weight loss, and annual preventive health visits. | Continue reading
This population-based cohort study compares the concentrations of biomarkers of nicotine and other toxicants of cigarettes and electronic cigarettes (e-cigarettes) in smokers who used one or both products vs individuals who have never used tobacco products. | Continue reading
This systematic review and meta-analysis synthesizes the available literature to evaluate the association between atopic dermatitis and suicidality. | Continue reading
This study describes using an unmodified iPhone X to conduct direct ophthalmoscopy. | Continue reading
This general population survey study evaluates the association between past 12-month exposure to police violence and concurrent mental health symptoms among urban residents in 2 US cities. | Continue reading
This cohort study investigates the differences in temporal synchrony between brain regions in individuals with autism and those with typical development. | Continue reading