Trends in Human Healthspan versus Lifespan – Fight Aging

Aging is damage, and the body fails in the same way that any complex, damaged machine fails. If one slows the pace of damage accumulation, as technological progress over the past century has achieved to a modest degree, albeit by accident rather than intent, both overall life spa … | Continue reading | 8 days ago

Alcor Position Statement on Aldehyde-Stabilized Cryopreservation

Cryonics provider Alcor have today published their position on aldehyde-stabilized cryopreservation. This is the vitrification methodology used by 21st Century Medicine to win the first stage of the Brain Preservation Prize earlier this month. The researchers demonstrated excepti … | Continue reading | 8 days ago

Request for Startups in the Rejuvenation Biotechnology Space

For a few years now, I've suggested areas of opportunity in rejuvenation biotechnology in which either (a) it seems quite viable to start a company, given what I've seen going on in industry and academia, or (b) it would be very helpful should someone step up with an approach tha … | Continue reading | 4 months ago

LookBack at 2020: Progress Towards the Treatment of Aging as a Medical Condition

While I suspect that COVID-19 will feature prominently in most retrospectives on 2020, I'll say only a little on it. The data on mortality by year end, if taken at face value, continues to suggest that the outcome will fall at the higher end of the early estimates of a pandemic t … | Continue reading | 5 months ago

A Coda to the C60 in Olive Oil Saga

The matter of buckminsterfullerene (C60) in olive oil is an instructive example of how bad work can lead a field astray for some time, but is ultimately squashed. Back in 2012, a paper was published claiming a sizable effect on life span in rats via treatment with C60 in olive oi … | Continue reading | 7 months ago

Impaired Insulin Signaling and Chronic Inflammation in the Alzheimer's Brain

In past years, there has been considerable discussion of Alzheimer's disease as a type 3 diabetes | Continue reading | 2 years ago

Oisin Biotechnologies Produces Impressive Mouse Life Span Data

Oisin Biotechnologies is the company working on what is, to my eyes, the best of the best when it comes to the current crop of senolytic technologies, approaches capable of selectively destroying senescent cells in old tissues. Adding senescent cells to young mice has been shown … | Continue reading | 2 years ago

The Fable of the Dragon-Tyrant, and the Courage to Oppose Aging

It has been thirteen years since Nick Bostrom published The Fable of the Dragon-Tyrant, a clear call to action regarding our relationship with aging and medical technology. The world has come to treat aging and the vast tide of death and suffering it causes as something set in s … | Continue reading | 3 years ago