Objective To examine the effect of regular breakfast consumption on weight change and energy intake in people living in high income countries.Design Systematic review and meta-analysis.Data sources PubMed, Ovid Medline, and CINAHL were searched for randomised controlled trials pu … | Continue reading
Neurosurgery is competitive so planning and preparation are crucial, say Fozia Saeed and Ian Anderson | Continue reading
Objective To assess the association between intake of non-sugar sweeteners (NSS) and important health outcomes in generally healthy or overweight/obese adults and children.Design Systematic review following standard Cochrane review methodology.Data sources Medline (Ovid), Embase, … | Continue reading
Susan Greenhalgh investigates how, faced with shrinking Western markets, the soft drink giant sought to secure sales and build its image in China Ever since 2001, when the US surgeon general called on all Americans to fight the newly named epidemic of obesity, the soft drink indu … | Continue reading
Objective To determine if using a parachute prevents death or major traumatic injury when jumping from an aircraft.Design Randomized controlled trial.Setting Private or commercial aircraft between September 2017 and August 2018.Participants 92 aircraft passengers aged 18 and over … | Continue reading
Forced harvesting of organs from prisoners of conscience in China has been “substantial,” says an interim judgment of an independent “people’s tribunal” set up to determine whether the country’s transplantation practices breached international criminal law.The former English judg … | Continue reading
Objective To determine the effects of diets varying in carbohydrate to fat ratio on total energy expenditure.Design Randomized trial.Setting Multicenter collaboration at US two sites, August 2014 to May 2017.Participants 164 adults aged 18-65 years with a body mass index of 25 or … | Continue reading
Objectives To determine whether parachutes are effective in preventing major trauma related to gravitational challenge.Design Systematic review of randomised controlled trials.Data sources: Medline, Web of Science, Embase, and the Cochrane Library databases; appropriate internet … | Continue reading
Objective To estimate the incidence of self report of pregnancy without sexual intercourse (virgin pregnancy) and factors related to such reporting, in a population representative group of US adolescents and young adults.Design Longitudinal, population representative sample surve … | Continue reading
Objectives To investigate whether the association between subjective wellbeing (subjective happiness and life satisfaction) and cardiometabolic health is causal.Design Two sample, bidirectional mendelian randomisation study.Setting Genetic data taken from various cohorts comprise … | Continue reading
Crowdfunding sites are helping people with advanced cancer spend thousands of pounds on unproved and alternative treatments. Melanie Newman examines calls to help ensure patients and their donors are not being exploitedDoctors face difficult conversations with patients with metas … | Continue reading
Objective To systematically compare midlife mortality patterns in the United States across racial and ethnic groups during 1999-2016, documenting causes of death and their relative contribution to excess deaths.Design Trend analysis of US vital statistics among racial and ethnic … | Continue reading
Objectives To determine the overall rate of loss of workplace teaspoons and whether attrition and displacement are correlated with the relative value of the teaspoons or type of tearoom.Design Longitudinal cohort study.Setting Research institute employing about 140 people.Subject … | Continue reading
Removing the cancer label in low risk conditions that are unlikely to cause harm if left untreated may help reduce overdiagnosis and overtreatment, argue Brooke Nickel and colleagues Evidence is mounting that disease labels affect people’s psychological responses and their decisi … | Continue reading
Objective To evaluate the relation between penicillin allergy and development of meticillin resistant Staphylococcus aureus (MRSA) and C difficile .Design Population based matched cohort study.Setting United Kingdom general practice (1995-2015).Participants 301 399 adults without … | Continue reading
It’s complicatedAlzheimer’s disease is a rapidly growing clinical and public health problem with currently no disease modifying therapies to treat or prevent the disease.1 Research suggests that pathological changes precede clinical symptoms by decades,2 resulting in an increased … | Continue reading