Although the Nazi genocide of Jews during World War II is well known, the concurrent Nazi genocide of psychiatric patients is much less widely known. An attempt was made to estimate the number of individuals with schizophrenia who were sterilized and ... | Continue reading
Designed a century ago to treat epilepsy, the ketogenic diet (KD) is also effective against obesity and diabetes. Paradoxically, some studies in rodents have found that the KD seemingly causes diabetes, contradicting solid clinical data in humans. This ... | Continue reading
Although advanced age or symptoms of aging are not among approved indications for growth hormone (GH) therapy, recombinant human GH (rhGH) and various GH-related products are aggressively promoted as anti-aging therapies. Well-controlled studies of the ... | Continue reading
Artificial intelligence (AI) has successfully made its way into contemporary industrial sectors such as automobiles, defense, industrial automation 4.0, healthcare technologies, agriculture, and many other domains because of its ability to act autonomously ... | Continue reading
Santiago Ramón y Cajal, a mythic figure in science and recognized as the father of modern anatomy and neurobiology, was largely responsible for the modern conception of the brain. The first to publish on the nervous system, he sought to educate ... | Continue reading
The historical evolution of infant feeding includes wet nursing, the feeding bottle, and formula use. Before the invention of bottles and formula, wet nursing was the safest and most common alternative to the natural mother's breastmilk. Society's negative ... | Continue reading
Anxiety, stress, and low mood are closely related and may contribute to depressive symptoms. Among non-pharmacological solutions to improve subclinical mood symptoms and resilience to stress, natural products such as saffron—identified as promising ... | Continue reading
Find SARS-CoV-2 related resources at NCBI. Download and submit sequences. Explore literature, identify clinical trials, and compounds used in them.(ncbi.nlm.nih.gov) | Continue reading
Four assumptions frequently arise in the aftermath of mass shootings in the United States: (1) that mental illness causes gun violence, (2) that psychiatric diagnosis can predict gun crime, (3) that shootings represent the deranged acts of mentally ill ... | Continue reading
Integration of legacy and third-party software systems is almost mandatory for enterprises. This fact is based mainly on exchanging information with other entities (banks, suppliers, customers, partners, etc.). That is why it is necessary to guarantee ... | Continue reading
Information technology outsourcing (ITO) is a USD multi-trillion industry. There is growing competition among ITO service providers to improve their service deliveries. Natural language processing (NLP) is a technique, which can be leveraged to gain a ... | Continue reading
Acetaminophen – a potent physical painkiller that also reduces empathy for other people’s suffering – blunts physical and social pain by reducing activation in brain areas (i.e. anterior insula and anterior cingulate) thought to ... | Continue reading
Nicotinamide mononucleotide (NNM) is an orally bioavailable NAD[+] precursor that has demonstrated beneficial effects against aging and aging-associated diseases in animal models. NMN is ultimately converted to NAD[+] , a redox cofactor that mediates ... | Continue reading
Human brown adipose tissue (BAT) has attracted clinical interest not only because it dissipates energy but also for its potential capacity to counteract obesity and related metabolic disorders (e.g., insulin resistance and dyslipidemia). Cold exposure ... | Continue reading
The importance of assessing evolutionarily relevant social cues suggests that humans should be sensitive to others' sleep history, as this may indicate something about their health as well as their capacity for social interaction. Recent findings show ... | Continue reading
It is generally assumed that dietary water might be beneficial for the health, especially in dermatological (age preventing) terms. The present study was designed to quantify the impact of dietary water on major indicators of skin physiology. A total ... | Continue reading
Ants use various communication channels to regulate their social organisation. The main channel that drives almost all the ants’ activities and behaviours is the chemical one, but it is long acknowledged that the acoustic channel also plays an ... | Continue reading
For some decades, the concept of human dignity has been widely discussed in bioethical literature. Some authors think that this concept is central to questions of respect for human beings, whereas others are very critical of it. It should be noted that, ... | Continue reading
Cerumen or earwax is an emerging bio-fluid in clinical diagnosis that has been very little exploited during the past decades in spite of its high diagnostic potential. It is highly abundant in diagnostic biomarkers such as genetic material, lipids, proteins, ... | Continue reading
Accumulating evidence suggests that nicotine, a drug that stimulates nicotinic acetylcholine receptors, may be of therapeutic value in Parkinson’s disease. Beneficial effects may be several-fold. One of these is a protective action against nigrostriatal ... | Continue reading
Alzheimer's diseases (AD) is the most common type of dementia and a neurodegenerative disease that occurs when the nerve cells in the brain die. The cause and treatment of AD remain unknown. However, AD is a disease that affects the brain, an organ that ... | Continue reading
The rule-based search of chemical space can generate an almost infinite number of molecules, but exploration of known molecules as a function of the minimum number of steps needed to build up the target graphs promises to uncover new motifs and transformations. ... | Continue reading
The habit of finger-licking is an insanitary habit observed everywhere including hospital wards and other medical facilities, among providers and other staff members. It is an enduring habit that has been present before and during the pandemic and will ... | Continue reading
Several Unidentified Aerial Phenomena (UAP) encountered by military, commercial, and civilian aircraft have been reported to be structured craft that exhibit ‘impossible’ flight characteristics. We consider a handful of well-documented ... | Continue reading
Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. ... | Continue reading
One fundamental feature of consciousness is that the contents of consciousness depend on the state of consciousness. Here, we propose an answer to why this is so: both the state and the contents of consciousness depend on the activity of cortical layer ... | Continue reading
Mammals have evolved a range of behavioural and neurological mechanisms that coordinate cycles of thermoregulation and sleep. Whether diurnal or nocturnal, sleep onset and a reduction in core temperature occur together. Non-rapid eye movement (NREM) sleep ... | Continue reading
Caffeine is a commonly used neurostimulant that also produces cerebral vasoconstriction by antagonizing adenosine receptors. Chronic caffeine use results in an adaptation of the vascular adenosine receptor system presumably to compensate for the vasoconstrictive ... | Continue reading
Over the last 50 years, we argue that incentives for academic scientists have become increasingly perverse in terms of competition for research funding, development of quantitative metrics to measure performance, and a changing business model for higher ... | Continue reading
Drug repositioning is a strategy for identifying new antitumor drugs; this strategy allows existing and approved clinical drugs to be innovatively repurposed to treat tumors. Based on the similarities between parasitic diseases and cancer, recent studies ... | Continue reading
Seroprevalence surveys suggest that more than a third and possibly more than half of the global population has been infected with SARS-CoV-2 by early 2022. As large numbers of people continue to be infected, the efficacy and duration of natural immunity ... | Continue reading
Spread of antibiotic resistance is mediated by clonal lineages of bacteria that besides being resistant also possess other properties promoting their success. Some vaccines already in use, such as the pneumococcal conjugate vaccines, have had an effect ... | Continue reading
The psychedelic alkaloid ibogaine has anti-addictive properties in both humans and animals.[] Unlike most substance use disorder (SUD) medications, anecdotal reports suggest that ibogaine possesses the potential to treat patients addicted to a variety ... | Continue reading