We are junior scientists from emerging economies — the world needs more researchers like us solving global problems

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02485-4 Scientific advancement relies on equitable international collaboration. And right now, it’s not equitable enough. | Continue reading


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Genetic links found to the world's biggest killer of new mothers

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02466-7 Genes associated with postpartum haemorrhage spotlight a hormone’s role in dangerous bleeding after childbirth. | Continue reading


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Elusive high-energy neutrinos spotted at LHC

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02465-8 Observations of electron neutrinos could allow physicists to test theories about the particles’ behaviour. | Continue reading


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Audio long read: Hope, despair and CRISPR — the race to save one woman’s life

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02480-9 The tragic quest to develop a gene-editing therapy for a rare neurodegenerative disease showcases the messy state of modern drug development. | Continue reading


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How the rose got its iconic fragrance

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02424-3 A bouquet of genes involved in making volatile compounds helps to produce the flower’s characteristic scent. | Continue reading


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Meet the retired scientists who collaborate with younger colleagues

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02482-7 Julie Gould learns that age is no barrier to enjoying interesting work and life opportunities in retirement. | Continue reading


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Seventh patient ‘cured’ of HIV: why scientists are excited

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02463-w A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus. | Continue reading


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Retraction notices are getting clearer — but progress is slow

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02423-4 Communications relating to retractions are often still opaque and lacking in detail, but an analysis finds some evidence of improvement. | Continue reading


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Effort to ‘Trump-proof’ US science grows, but will it succeed?

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02484-5 Unions are joining the Biden administration’s campaign to promote scientific integrity and protect government scientists from political interference. | Continue reading


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Strokes can damage the heart — but reining in the immune system might help

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02426-1 Heart injury is reduced in mice when the cells that trigger inflammation are blocked. | Continue reading


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Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus

Nature, Published online: 26 July 2024; doi:10.1038/s41586-024-07845-8 Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus | Continue reading


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Three ways AI is changing the 2024 Olympics for athletes and fans

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02427-0 From training to broadcasting, artificial intelligence will have an imprint on this year’s event for the first time. | Continue reading


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DeepMind hits milestone in solving maths problems — AI’s next grand challenge

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02441-2 AlphaProof showed its prowess on questions from this year’s Mathematical Olympiad — a step in the race to create substantial proofs with artificial intelligence. | Continue reading


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V. Craig Jordan obituary: pharmacologist who revolutionized breast cancer treatments

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02448-9 Pioneer of targeted therapy in cancer who turned failed contraceptive tamoxifen into an essential drug for treating breast cancer and osteoporosis. | Continue reading


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India budget: Modi bets big on nuclear energy and space

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02370-0 The government has focused on areas of national pride and applied science, as many researchers expected. | Continue reading


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AI is vulnerable to attack. Can it ever be used safely?

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02419-0 The models that underpin artificial-intelligence systems such as ChatGPT can be subject to attacks that elicit harmful behaviour. Making them safe will not be easy. | Continue reading


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These brain cells help days-old mice to bond with mum

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02470-x Scientists pinpoint neurons that encode the mother–baby bond in the brains of infant mice. | Continue reading


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AI models fed AI-generated data quickly spew nonsense

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02420-7 Researchers gave successive versions of a large language model information produced by previous generations of the AI — and observed rapid collapse. | Continue reading


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SMYD5 methylation of rpL40 links ribosomal output to gastric cancer

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07718-0 The lysine methyltransferase SMYD5 and its newly identified substrate ribosomal protein L40 are implicated in the progression of gastric adenocarcinoma, and ablation of SMYD5 prevents metastatic disease in mou … | Continue reading


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TMEFF1 is a neuron-specific restriction factor for herpes simplex virus

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07670-z A study identifies TMEFF1 as a neuron-specific restriction factor essential for prevention of replication of herpes simplex virus type 1 in the central nervous system. | Continue reading


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In vivo interaction screening reveals liver-derived constraints to metastasis

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07715-3 Interactions between plexin B2 on hepatocytes and sempahorins on disseminated tumour cells regulate metastatic seeding in the liver. | Continue reading


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peri-Fused polyaromatic molecular contacts for perovskite solar cells

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07712-6 A peri-fused polyaromatic core structure is used to produce a relatively chemically inert and structurally rigid molecular contact that improves the efficiency and durability of perovskite solar cells. | Continue reading


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Global atmospheric methane uptake by upland tree woody surfaces

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07592-w Studies of in situ woody surface methane exchange in upland tropical, temperate and boreal forest trees find that methane uptake can result in a net tree methane sink that is globally significant and demonstra … | Continue reading


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Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07752-y Type 1 regulatory T cells (Tr1) represent a major obstacle that compromises naturally occurring and therapeutically induced tumour-specific immunity. | Continue reading


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Multi-heterojunctioned plastics with high thermoelectric figure of merit

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07724-2 Thermoelectric plastics with a high figure of merit, suppressed thermal conductivity and an enhanced power factor are realized by combining layered and bulk heterojunctions to create a polymeric multi-heteroju … | Continue reading


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Single-cell multiregion dissection of Alzheimer’s disease

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07606-7 A regional atlas of the ageing human brain—spanning six distinct anatomical regions from individuals with and without Alzheimer’s dementia—provides insights into cellular vulnerability, response and resilience … | Continue reading


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Human TMEFF1 is a restriction factor for herpes simplex virus in the brain

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07745-x A study of two childhood cases of herpes simplex encephalitis shows that TMEFF1 interacts with the HSV-1 cell-surface receptor NECTIN-1, preventing HSV-1 from fusing with the cell membrane and entering cortica … | Continue reading


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Shifts in receptors during submergence of an encephalitic arbovirus

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07740-2 Knockout studies using CRISPR–Cas9 identify PCDH10 as a selective host cellular receptor for western equine encephalitis virus. | Continue reading


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Molecular basis of human noradrenaline transporter reuptake and inhibition

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07719-z The cryo-electron microscopy structures of the human noradrenaline transporter in both the apo state and bound to substrates or antidepressant drugs are resolved. | Continue reading


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Jurassic fossil juvenile reveals prolonged life history in early mammals

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07733-1 Juvenile and adult skeletons of Middle Jurassic Krusatodon from the Isle of Skye, Scotland, show that this mouse-sized mammaliaform had longer development and lifespan than modern mammals of similar mass. | Continue reading


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Global net climate effects of anthropogenic reactive nitrogen

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07714-4 A comprehensive model framework is used to estimate the global net direct radiative forcing of anthropogenic reactive nitrogen as being about −0.34 W m−2, which has a cooling effect on the climate. | Continue reading


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Deep, hot, ancient melting recorded by ultralow oxygen fugacity in peridotites

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07603-w Analysis of peridotites reveals ultralow oxygen fugacity, suggesting that rafts of ancient, ultrareduced mantle were generated by deep melting at high temperatures and continue to circulate in the modern mantl … | Continue reading


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Cultivation and visualization of a methanogen of the phylum Thermoproteota

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07631-6 We demonstrate that the ability to conserve energy coupled to methane production is not restricted to the Euryarchaeota and is much more widespread than originally thought. | Continue reading


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Isolation of a methyl-reducing methanogen outside the Euryarchaeota

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07728-y Methanosuratincola petrocarbonis LWZ-6 is a strict hydrogen-dependent methylotrophic methanogen that does not ferment sugars, peptides or amino acids. | Continue reading


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A human autoimmune organoid model reveals IL-7 function in coeliac disease

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07716-2 A human in vitro model of coeliac disease comprising duodenal organoids that maintain both epithelium and an immune microenvironment finds a previously unsuspected role for IL-7 in gluten-induced epithelial de … | Continue reading


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Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07720-6 Cryo-electron microscopy, in vitro reconstitution and molecular dynamics simulations provide insight into the architecture of a plasma membrane microdomain in yeast, the organization and dynamics of the membra … | Continue reading


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Blood culture-free ultra-rapid antimicrobial susceptibility testing

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07725-1 An ultra-rapid antimicrobial susceptibility testing method is introduced that bypasses the need for traditional blood culture, demonstrating the potential to significantly reduce the turnaround time of reporti … | Continue reading


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AI models collapse when trained on recursively generated data

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07566-y Analysis shows that indiscriminately training generative artificial intelligence on real and generated content, usually done by scraping data from the Internet, can lead to a collapse in the ability of the mod … | Continue reading


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Rapid sepsis test identifies bacteria that spark life-threatening infection

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02462-x New method can help guide treatment with most effective antibiotic — plus how things get weird when an AI is trained on AI-created text. | Continue reading


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Publisher Correction: Tautomeric mixture coordination enables efficient lead-free perovskite LEDs

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07844-9 Publisher Correction: Tautomeric mixture coordination enables efficient lead-free perovskite LEDs | Continue reading


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Carbon pricing reduces emissions

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02293-w A meta-analysis of 21 carbon-pricing schemes suggests that the strategy reduces greenhouse-gas emissions. Deciding how high to set prices is the next step — and one that might benefit from the insights of less … | Continue reading


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Why you should perform a premortem on your research

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02344-2 Carsten Lund Pedersen introduces a tool for improving the success rate of your papers, projects and partnerships. | Continue reading


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The ape Y chromosome evolves extremely rapidly, but the X chromosome is conserved

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02404-7 The ape sex chromosomes have now been fully sequenced. Rapid evolution has led to extreme differences in the Y chromosome between species, whereas the X chromosome experienced much less dynamic changes. The pa … | Continue reading


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Every part of you

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02388-4 How to be happy? | Continue reading


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How do placebos ease pain? Mouse brain study offers clues

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02439-w The discovery of a brain circuit involved in the pain-relieving effect of placebos could lead to new treatments. | Continue reading


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Memory for music doesn’t diminish with age

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02369-7 Eighty-year-olds are able to identify familiar tunes just as well as teenagers can. | Continue reading


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So you got a null result. Will anyone publish it?

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02383-9 Researchers have tried a bunch of strategies to get more negative results into the literature. Nature asks whether they are working. | Continue reading


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Motor neurons move a fly’s head in different directions depending on its starting posture

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02401-w Motor neurons control the muscles and are therefore the only means through which the brain can move the body and interact with the world. The finding that motor neurons move a fly’s body differently depending … | Continue reading


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