How the brain separates real images from those it imagines

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01752-2 Neuroscientists have found the regions that keep them apart. | Continue reading


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Remote activation of place codes by gaze in a highly visual animal

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09101-z Place cells in the chickadee hippocampus coherently represent locations in space, whether physically visited or viewed, enabling spatial reasoning at a distance through a unified process coordinated by head sa … | Continue reading


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When do girls fall behind in maths? Gigantic study pinpoints the moment

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01831-4 Analysis of almost three million children captures when ‘mathematical gender gap’ first emerges and could help focus efforts to stop girls from falling behind. | Continue reading


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Cheat-proof random numbers generated from quantum entanglement

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01451-y A quantum random-number generator has been developed that uses classical cryptography to certify that its output was produced by a quantum process. | Continue reading


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Gene therapy could correct blood stem cells inside, rather than outside, the body

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01779-5 Experiments in mice reveal an early postnatal window of opportunity for the effective transfer of genes to blood-cell-producing haematopoietic stem cells by injecting mice with gene-carrying lentiviral vectors … | Continue reading


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Early life high fructose impairs microglial phagocytosis and neurodevelopment

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09098-5 Exposure of mice to high fructose during gestation or early postnatal life causes decreased microglial phagocytosis during brain development and leads to anxiety-like behaviour in adolescence. | Continue reading


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A fully open AI foundation model applied to chest radiography

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09079-8 Ark+, a fully open artificial intelligence foundation model, demonstrates exceptional capabilities in diagnosing common, rare and novel thoracic diseases. | Continue reading


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Rapid emergence of a maths gender gap in first grade

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09126-4 Boys and girls exhibit very similar maths scores upon school entry, but a gender gap in favour of boys becomes highly significant after 4 months of schooling, which increases with years of schooling, independe … | Continue reading


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Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09090-z An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose current production i … | Continue reading


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Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09111-x A study finding an oestrogen-sensing signalling pathway that promotes melanoma metastasis only in female mice emphasizes the importance of recognizing sex-specific factors in cancer management. | Continue reading


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Metabolic adaptations direct cell fate during tissue regeneration

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09097-6 Metabolic enzymes of the tricarboxylic acid cycle, such as 2-oxoglutarate dehydrogenase, are differentially expressed in absorptive and secretory lineages, guiding cell fate establishment and offering insights … | Continue reading


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Dynamic assemblies and coordinated reactions of non-homologous end joining

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09078-9 Structures associated with the final steps of non-homologous end joining (NHEJ) and gap filling present new targets for NHEJ inhibition to enhance efficacy of radiotherapy and accuracy of gene editing. | Continue reading


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Physical restoration of a painting with a digitally constructed mask

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09045-4 A digital restoration technique for damaged paintings was developed, in which a colour-accurate bilayer mask of printed pigments on polymeric films was used, reducing treatment time and cost while adhering to … | Continue reading


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Brain implantation of soft bioelectronics via embryonic development

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09106-8 A soft mesh microelectrode array can seamlessly integrate in developing brains, enabling long-term, stable mapping of how single-neuron activity and population dynamics emerge and evolve during brain developme … | Continue reading


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A new Mongolian tyrannosauroid and the evolution of Eutyrannosauria

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-08964-6 A new tyrannosauroid, Khankhuuluu mongoliensis gen. et sp. nov., from lower Upper Cretaceous deposits of Mongolia provides a new perspective on eutyrannosaurian origins and evolution. | Continue reading


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Abyssal seafloor as a key driver of ocean trace-metal biogeochemical cycles

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09038-3 Rare earth element and neodymium isotope data combined with models of particle cycling and sediment diagenesis suggest that the abyssal seafloor is a key driver of trace-metal biogeochemical cycles. | Continue reading


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Weakly space-confined all-inorganic perovskites for light-emitting diodes

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09137-1 Weakly space-confined, large-grained crystals of all-inorganic perovskite were used to fabricate light-emitting diodes with a high external quantum efficiency and operational stability. | Continue reading


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Traceable random numbers from a non-local quantum advantage

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09054-3 A study demonstrates a public generator of random numbers based on device-independent techniques, with the randomness being fully auditable and traceable. | Continue reading


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Molecular hydrogen in the extremely metal- and dust-poor galaxy Leo P

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09115-7 Observations from the JWST MIRI-MRS instrument reveal the detection of rotational emission from molecular hydrogen near the only O-type star in the 3% solar metallicity galaxy Leo P, providing confirmation tha … | Continue reading


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Probing phonon transport dynamics across an interface by electron microscopy

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09108-6 In situ vibrational electron energy-loss spectroscopy is used to examine phonon transport dynamics across the AlN–SiC interface during thermal transport at sub-nanometre resolution, demonstrating a sharp tempe … | Continue reading


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Preparation of a neutral nitrogen allotrope hexanitrogen C2h-N

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09032-9 The facile synthesis and spectroscopic identification of previously unreported hexanitrogen C2h-N6 is described, representing experimentally realized neutral molecular nitrogen allotropes beyond N2 that exhibi … | Continue reading


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Developmental trajectory and evolutionary origin of thymic mimetic cells

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09148-y In mice, tissue-mimetic cells appear in thymus in two distinct waves, creating two distinct pools of mimetic cells, each expressing antigens characteristic of different cell types. | Continue reading


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RIFINs displayed on malaria-infected erythrocytes bind KIR2DL1 and KIR2DS1

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09091-y Certain RIFINs from Plasmodium falciparum can bind to both inhibitory (KIR2DL1) and activating (KIR2DS1) immune receptors on natural killer cells, demonstrating the potential role of activating killer immunogl … | Continue reading


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Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09162-0 Lipoprotein uptake dependent on sulfated glycosaminoglycans linked to cell-surface proteoglycans is a key determinant of ferroptosis sensitivity in cancer. | Continue reading


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Attosecond inner-shell lasing at ångström wavelengths

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09105-9 Strong lasing effects similar to those in the optical regime can occur at 1.5–2.1 Å wavelengths during high-intensity XFEL-driven Kα1 lasing of copper and manganese. | Continue reading


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A complementary two-dimensional material-based one instruction set computer

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-08963-7 A two-dimensional one instruction set computer has been fabricated based on complementary metal–oxide–semiconductor technology by leveraging the heterogeneous integration of large-area n-type MoS2 and p-type W … | Continue reading


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A neutral-atom Hubbard quantum simulator in the cryogenic regime

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09112-w A several-fold reduction in temperature is accomplished using a neutral-atom Hubbard quantum simulator by transforming a low-entropy product state into strongly correlated states of interest via dynamic contro … | Continue reading


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SP140–RESIST pathway regulates interferon mRNA stability and antiviral immunity

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09152-2 The antiviral protein SP140 negatively regulates Ifnb1 mRNA stability by directly repressing the expression of the immune regulator RESIST. | Continue reading


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Meet the MIT engineer who invented an AI-powered way to restore art

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01836-z The new method could be 70 times faster than repairing painting by hand. | Continue reading


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This stretchy neural implant grows with an axolotl's brain

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01850-1 The flexible implant measures brain activity during embryonic development in amphibians — plus, a new way to restore damaged paintings with the help of AI. | Continue reading


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Quantum physicists unveil most ‘trustworthy’ random-number generator yet

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01849-8 Upgraded system produces strings of random bits in a process that is fully traceable. | Continue reading


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A cancer-causing mutation meets its match

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01801-w In mice, engineered immune cells shrink pancreatic and other tumours bearing a mutant version of the KRAS protein. | Continue reading


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NIH chief stands by funding cuts to ‘politicized science’ at tense hearing

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01827-0 Jayanta Bhattacharya says the US biomedical agency can’t continue ‘business as usual’ if it wants to restore its reputation. | Continue reading


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To progress, science must be truly global

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01769-7 Building scientific capacity in the global south is key to solving today’s most pressing planetary challenges. | Continue reading


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How to keep weight off after obesity drugs

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01770-0 Options are emerging for the tens of millions of people who stop taking GLP-1 drugs because of side effects, cost or availability. | Continue reading


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Digging foxholes in the dark

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01778-6 A safe place. | Continue reading


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Major telescope hosts world's largest digital camera: how it will transform astronomy

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01798-2 Massive telescope will map the Universe and provide an evolving record of the Solar System and distant stars. | Continue reading


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Greening nickel extraction requires institutional and financial support

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01811-8 Greening nickel extraction requires institutional and financial support | Continue reading


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Reduced investment in universities has multifaceted effects

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01809-2 Reduced investment in universities has multifaceted effects | Continue reading


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Not all clinical data in the United States are fragmented

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01810-9 Not all clinical data in the United States are fragmented | Continue reading


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Making concrete sustainable globally requires technology transfer

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01812-7 Making concrete sustainable globally requires technology transfer | Continue reading


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How to speak to a vaccine sceptic: research reveals what works

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01771-z Hesitancy about vaccinations is on the rise, but studies show there are specific ways to overcome people’s doubts. | Continue reading


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This tiny device spins blood clots away

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01815-4 An unexpected discovery could lead to safer surgical interventions for strokes | Continue reading


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Peter Lax obituary: mathematician who pioneered computer-based solutions to real-world problems

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01837-y The Abel prizewinner’s pragmatic approach to solving differential equations was influential across fields ranging from weather forecasting to starting nuclear chain reactions. | Continue reading


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Mathematics in ancient Egypt

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01585-z Calculation principles found in a papyrus scroll, and an author shares his love of lichens in this week’s pick from the Nature archive. | Continue reading


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Stressed out by PhD life? Five strategies to take back the joy

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01225-6 Doing a PhD is really hard. Here’s how I’ve learnt to enjoy the process. | Continue reading


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Daily briefing: Evidence-backed strategies for talking about vaccine hesitancy

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01847-w Experts share tips for talking about vaccines with your inner circle. Plus, a tiny device that ‘spins’ blood clots away and why so many attempts to reduce fossil-fuel subsidies fail — and what to do about it. | Continue reading


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Dementia is deadly — the UN needs to take it more seriously

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01768-8 Improved recognition of dementia as a major non-communicable disease by multilateral organizations is crucial, to build awareness and increase funding to tackle this insidious illness. | Continue reading


@nature.com | 2 days ago