Embryonic genome instability upon DNA replication timing program emergence

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07841-y A single-cell genome-wide DNA replication atlas of pre-implantation mouse embryos reveals an abrupt replication program switch accompanied by a transient period of genomic instability. | Continue reading


@nature.com | 2 months ago

Spatially clustered type I interferon responses at injury borderzones

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07806-1 Cardiomyocytes are the dominant initiators of a type I interferon response in the infarct borderzone. | Continue reading


@nature.com | 2 months ago

Fate induction in CD8 CAR T cells through asymmetric cell division

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07862-7 We show that target-induced proximity labelling enables isolation of first-division CD8 chimeric antigen receptor T cells that asymmetrically distribute their surface proteome and transcriptome, resulting in … | Continue reading


@nature.com | 2 months ago

A population code for spatial representation in the zebrafish telencephalon

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07867-2 Using a tracking microscope for freely moving animals, the authors discover a population of place cells in the zebrafish brain and demonstrate that a non-amniote brain is capable of integrating allothetic an … | Continue reading


@nature.com | 2 months ago

Earth’s ambipolar electrostatic field and its role in ion escape to space

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07480-3 The ambipolar field of Earth controls the structure of the polar ionosphere and boosts its scale height by 271%, physically driving the polar wind and acting as the source of the magnetospheric cold H+ ion p … | Continue reading


@nature.com | 2 months ago

Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07871-6 A comprehensive cell atlas of the aged prefrontal cortex identifies two distinct cellular trajectories of ageing driven by specific glial and neuronal subpopulations, some of which are associated with clinic … | Continue reading


@nature.com | 2 months ago

Signatures of hybridization of multiple Majorana zero modes in a vortex

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07857-4 We observe signatures of the existence and hybridization of multiple Majorana zero modes in a single vortex. | Continue reading


@nature.com | 2 months ago

Long-lived isospin excitations in magic-angle twisted bilayer graphene

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07880-5 A combination of exciton sensing and optical pump–probe spectroscopy is used to investigate the dynamics of isospin orders in MATBG with WSe2 substrate across the entire flat band, achieving sub-picosecond r … | Continue reading


@nature.com | 2 months ago

Carbon emissions from the 2023 Canadian wildfires

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07878-z Satellite carbon monoxide observations show that carbon emissions from the 2023 Canadian forest fires are comparable to the annual fossil fuel emissions of large nations. | Continue reading


@nature.com | 2 months ago

To remain modern the coexistence program requires modern statistical rigour

Nature, Published online: 28 August 2024; doi:10.1038/s41586-023-06919-3 To remain modern the coexistence program requires modern statistical rigour | Continue reading


@nature.com | 2 months ago

M. N. Van Dyke et al. reply

Nature, Published online: 28 August 2024; doi:10.1038/s41586-024-07777-3 M. N. Van Dyke et al. reply | Continue reading


@nature.com | 2 months ago

Uncertain competition coefficients undermine inferences about coexistence

Nature, Published online: 28 August 2024; doi:10.1038/s41586-023-06859-y Uncertain competition coefficients undermine inferences about coexistence | Continue reading


@nature.com | 2 months ago

Covert racism in AI chatbots, precise Stone Age engineering, and the science of paper cuts

Nature, Published online: 28 August 2024; doi:10.1038/d41586-024-02806-7 We round up some recent stories from the Nature Briefing. | Continue reading


@nature.com | 2 months ago

What accelerates brain ageing? This AI 'brain clock' points to answers

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02770-2 Exposure to air pollution and living in a country with high socioeconomic inequality are linked to a bigger gap between brain age and chronological age. | Continue reading


@nature.com | 2 months ago

AI firms must play fair when they use academic data in training

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02757-z Researchers are among those who feel uneasy about the unrestrained use of their intellectual property in training commercial large language models. Firms and regulators need to agree the rules of engagement. | Continue reading


@nature.com | 2 months ago

No more hunting for replication studies: crowdsourced database makes them easy to find

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02598-w Project co-leader explains why the social sciences needs a database that links reproducibility efforts to the original studies. | Continue reading


@nature.com | 2 months ago

Local politicians have opened up Europe’s largest marine reserve for commercial fishing

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02754-2 Local politicians have opened up Europe’s largest marine reserve for commercial fishing | Continue reading


@nature.com | 2 months ago

Urgently clarify how AI can be used in medicine under new EU law

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02753-3 Urgently clarify how AI can be used in medicine under new EU law | Continue reading


@nature.com | 2 months ago

Binning out-of-date chemicals? Somebody think about the carbon!

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02755-1 Binning out-of-date chemicals? Somebody think about the carbon! | Continue reading


@nature.com | 2 months ago

Indian landslide tragedy demands a rethink of hazard mapping in a changing climate

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02752-4 Indian landslide tragedy demands a rethink of hazard mapping in a changing climate | Continue reading


@nature.com | 2 months ago

Scientists, your local communities need you. It’s time to step up

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02758-y Researchers and engineers have the skills, and often the desire, to get involved with local policymaking efforts. They should take the plunge; it’s easier and more rewarding than it might seem. | Continue reading


@nature.com | 2 months ago

Man versus horse: who wins?

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02667-0 An interspecies endurance test, and a defence of Darwin’s reticence on the origins of life, in this week’s snippets from Nature’s past. | Continue reading


@nature.com | 2 months ago

The cool technologies that could protect cities from dangerous heat

Nature, Published online: 27 August 2024; doi:10.1038/d41586-024-02760-4 From supercool materials that send heat into space to shape-shifting materials that can selectively fend it off, scientists are finding new strategies to reduce urban temperatures. | Continue reading


@nature.com | 2 months ago

The meaning of the Anthropocene: why it matters even without a formal geological definition

Nature, Published online: 26 August 2024; doi:10.1038/d41586-024-02712-y Even though geologists have rejected the designation of an Anthropocene epoch, the idea of a major planetary transition in the mid-twentieth century remains useful across physical and social sciences, the hu … | Continue reading


@nature.com | 2 months ago

Mysterious Oropouche virus is spreading: what you should know

Nature, Published online: 26 August 2024; doi:10.1038/d41586-024-02746-2 The virus is endemic to the Amazon but is now spreading outside the region ― and has been linked to human deaths for the first time. | Continue reading


@nature.com | 2 months ago

Birth of protein folds and functions in the virome

Nature, Published online: 26 August 2024; doi:10.1038/s41586-024-07809-y Structural comparison of predicted viral protein structures with known protein structures suggests taxonomic relationships and functions for up to 25% of unannotated viral proteins, including many with putat … | Continue reading


@nature.com | 2 months ago

How I create virtual twins for fabrics and furniture

Nature, Published online: 26 August 2024; doi:10.1038/d41586-024-02763-1 Jakub Cech creates digital versions of materials for use in the virtual world. | Continue reading


@nature.com | 2 months ago

Stone Age builders had engineering savvy, finds study of 6000-year-old monument

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02776-w A survey of the Dolmen of Menga suggests that the stone tomb’s Neolithic builders had an understanding of science. | Continue reading


@nature.com | 2 months ago

How to harness AI’s potential in research — responsibly and ethically

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02762-2 Artificial intelligence is propelling advances in all areas of science. But vigilance is needed, warn four researchers at the leading edge. | Continue reading


@nature.com | 2 months ago

Partners in drug discovery: how to collaborate with non-governmental organizations

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02774-y Not all researchers join forces with big pharmaceutical firms, non-profit groups can help take lifesaving findings to where they are needed most. | Continue reading


@nature.com | 2 months ago

AI analysed 1,500 policies to cut emissions. These ones worked

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02717-7 Only 63 climate change interventions led to significant reductions in carbon emissions. | Continue reading


@nature.com | 2 months ago

Lactate helps cancer cells resist chemotherapy

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02731-9 The molecule lactate is a waste product of the metabolism of sugar without oxygen — a metabolic pathway preferentially used by cancer cells to generate their energy. Metabolomics analysis reveals that lactat … | Continue reading


@nature.com | 2 months ago

Fall of the wild: why pristine wilderness is a human-made myth

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02761-3 Even ‘untouched’ natural landscapes bear witness to millennia of human influence, a lyrical book argues — with implications for how we seek to rewild them. | Continue reading


@nature.com | 2 months ago

Ancient equine genomes reveal dawn of horse domestication

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02734-6 An analysis of ancient genomes reveals an explosive geographical and demographic spread of modern domestic horses about 4,200 years ago. The findings counter the idea that horses accompanied and mobilized th … | Continue reading


@nature.com | 2 months ago

Story time

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02764-0 Family matters. | Continue reading


@nature.com | 2 months ago

What Science and Nature are good for: causing paper cuts

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02297-6 Experiments reveal that human skin is most reliably cut by specific thicknesses of paper, including the kind used to print certain high-profile journals. | Continue reading


@nature.com | 2 months ago

Science treasures from Microsoft mogul up for auction — and researchers are salivating

Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02769-9 Spacesuits, historic computers and more from the estate of the late Paul Allen are going on sale. | Continue reading


@nature.com | 2 months ago

‘I hope I get the opportunity to fly’: Meet Paralympian-turned-astronaut John McFall

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02728-4 Nature speaks to the world’s first disabled astronaut about his hopes for the future of space exploration. | Continue reading


@nature.com | 2 months ago

This unlucky star got mangled by a black hole — twice

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02654-5 Bursts of light hint that a star in a nearby galaxy was partially shredded in 2022 and 2024 and might be in for another round. | Continue reading


@nature.com | 2 months ago

Daily briefing: It’s not the fasting, it’s the eating

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02779-7 Fasting’s regenerative powers kick in when the feasting starts. Plus, future plans for detecting gravitational waves and an energy-rating scheme for artificial intelligence systems. | Continue reading


@nature.com | 2 months ago

AI made of jelly ‘learns’ to play Pong — and improves with practice

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02704-y Inspired by neurons in a dish playing the classic video game, researchers show that synthetic hydrogels have a basic ‘memory’. | Continue reading


@nature.com | 2 months ago

Debate rages over Alzheimer’s drug lecanemab as UK limits approval

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02720-y The medicine is being assessed by agencies including the European Union regulator, but the community is divided on its efficacy and safety. | Continue reading


@nature.com | 2 months ago

Don’t stop me now: Queen’s Brian May on saving badgers — and the scientific method

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02729-3 The guitarist has spent a decade studying the science of bovine tuberculosis and identified a new method of spread. | Continue reading


@nature.com | 2 months ago

Extreme heat is a huge killer — these local approaches can keep people safe

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02705-x As the threat of deadly heatwaves rises, scientists are working with cities to introduce low-tech cooling features to protect citizens. | Continue reading


@nature.com | 2 months ago

Can ageing be stopped? A biologist explains

Nature, Published online: 22 August 2024; doi:10.1038/d41586-024-02713-x Nobel laureate Venki Ramakrishnan joins us to talk about his book Why We Die: The New Science of Ageing and the Quest for Immortality. | Continue reading


@nature.com | 2 months ago

The surprising cause of fasting’s regenerative powers

Nature, Published online: 21 August 2024; doi:10.1038/d41586-024-02700-2 Post-fast feasting helps to activate stem cells in the gut but can also prompt development of precancerous growths, mouse research shows. | Continue reading


@nature.com | 2 months ago

First biolab in South America for studying world’s deadliest viruses is set to open

Nature, Published online: 21 August 2024; doi:10.1038/d41586-024-02609-w Construction is underway for the maximum-security Brazilian facility, which will face cost and regulatory hurdles. | Continue reading


@nature.com | 2 months ago

Planet Earth turns slowly

Nature, Published online: 21 August 2024; doi:10.1038/d41586-024-02461-y Home from home. | Continue reading


@nature.com | 2 months ago