Nature, Published online: 08 August 2024; doi:10.1038/d41586-024-02563-7 Study of more than ten million people suggests that early gestation is the most vulnerable time to be exposed to malnutrition. | Continue reading
Nature, Published online: 08 August 2024; doi:10.1038/d41586-024-02583-3 The International Court of Justice is set to clarify the responsibilities of states to act on global warming. Governments must step up in support — before it’s too late. | Continue reading
Nature, Published online: 08 August 2024; doi:10.1038/d41586-024-02557-5 Stress leads to disarray of the gut microbiome, which in turn causes inflammation and a drop in the body’s ability to fend off infection. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02454-x A holiday to remember. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02521-3 Cybercriminals are increasingly singling out researchers, alongside politicians and celebrities. Targeted scientists share tips on how to silence them. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02546-8 Sensors mounted on the animals’ backs gather data on unexplored sea floor habitats. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02572-6 Migrating cells must determine where to form a front end and a back end. A gradient in contact sites between the cell membrane and an organelle called the endoplasmic reticulum (ER) is generated by a gradien … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02506-2 Microbe found in cat poo could be harnessed to deliver large, complex proteins across the blood–brain barrier. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02234-7 Cells that form tissue barriers rely on cell–cell contacts called tight junctions. These structures assemble from protein condensates that spread along the cell membrane like a water droplet spreading over g … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02578-0 As environments get more dry, plant species numbers drop, but the number of traits increase — plus, what the hottest temperatures for centuries mean for the Great Barrier Reef. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07746-w Disruption of leukaemia inhibitory factor production from group 2 innate lymphoid cells prevents immune cells leaving the lungs to migrate to lymph nodes, leading to plasmacytoid dendritic cells becoming ret … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07793-3 A comprehensive spatial expression atlas of the adult human proximal small intestine reveals branched villi, immune activation at the villus tip, and a switch of migrating enterocytes from lipid droplet asse … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07722-4 A cross-reactive antibody and T cell response is identified in a large portion of patients with multisystem inflammatory syndrome in children. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07687-4 We present fully forward mode learning, which conducts machine learning operations on site, leading to faster learning and promoting advancement in numerous fields. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07786-2 By using intercalative oxidation techniques, stable, stoichiometric and atomically thin single-crystalline Al2O3 films can be produced, which can be effectively used as a dielectric in top-gated field-effect … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07767-5 Hyperactivation of sensory neurons regulates multiple aspects of metastatic progression in breast cancer. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07731-3 Analysis of 20 chemical and morphological plant traits at diverse sites across 6 continents shows that the transition from semi-arid to arid zones is associated with an unexpected 88% increase in trait diver … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07672-x High ocean temperatures that caused mass coral bleaching and mortality on the Great Barrier Reef in the past decade are the warmest in 400 years and are the result of human-caused climate change. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07788-0 An example of hybrid incompatibility between maize and teosinte reveals a selfish toxin–antidote system mediated by small RNAs that may have contributed to the origin of maize. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07804-3 A study using cryo-electron microscopy has determined the structure of the human dopamine transporter with bound cocaine, revealing molecular details about neurotransmitter transport and how it is affected b … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07797-z Oncogenic RAS dose-escalation models are used to explore how the level of RAS determines whether cells enter a senescent state or have tumour-initiating activity. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07769-3 A large integrated genome and transcriptome analysis of colorectal cancer identifies prognostic mutations and expression subtypes. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07717-1 By integrating geological observations, statistical analysis, geodynamic simulations and landscape-evolution models, a physical model is proposed to link the coevolution of craton margins and interiors with … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07801-6 The orphan enzyme phosphotriesterase-related (PTER) is identified as a mammalian N-acetyltaurine hydrolase that has roles in regulating body weight and energy balance. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07747-9 Whole-genome sequencing of more than 2,000 colorectal carcinoma samples provides a highly detailed view of the genomic landscape of this cancer and identifies new driver mutations. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07726-0 Experimental and theoretical results demonstrate that tight-junction formation depends on the growth of a condensed layer of ZO-1 proteins at the interface of the apical and lateral membrane, providing insig … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07782-6 Observations of a third, less luminous persistent radio source associated with the repeating fast radio burst FRB 20201124A indicate that the burst originates from a young magnetar surrounded by a nebula of … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07787-1 Functional genomics and lipidomic analyses reveal that sphingolipid synthesis is required for tumour immune evasion and tumour growth in vivo, mediated in part by the impact of glycosphingolipid synthesis on … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07803-4 This study describes sensing of circulating cell-free DNA after stroke as the mechanism leading to recurrent ischemic events. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07772-8 The bacterial phage anti-restriction-induced system, PARIS, operates as a toxin–antitoxin system, in which the antitoxin AriA sequesters and inactivates the toxin AriB until triggered by the T7 phage counter … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07784-4 Structures of the growing peptide chain on and off the ribosome reveal that the ribosome destabilizes the unfolded nascent chain, promoting the formation of partially folded intermediate states. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07796-0 Structural analyses of the human dopamine transporter in apo and substrate-bound states and in complex with drugs and inhibitors reveal key binding residues and conformational transitions that occur during s … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07739-9 Cryo-electron microscopy structure of the human dopamine transporter in complex with multiple inhibitors illuminates mechanisms of allosteric inhibition. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07874-3 A virally-encoded tRNA neutralizes the PARIS antiviral defence system | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/s41586-024-07904-0 Author Correction: Senescent glia link mitochondrial dysfunction and lipid accumulation | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02535-x Scientists are closing in on biomarkers that reflect the progression of Alzheimer’s disease and could improve treatments. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02564-6 Molecular, anatomical and functional evidence point to a multi-nodal neural circuit that senses allergenic particles in inhaled air and induces exaggerated airway constriction, a hallmark of asthma. This is … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02561-9 The two strands of DNA, although chemically equivalent, are replicated and repaired asymmetrically. Insights into the persistence of DNA damage show how strand-specific interactions shape the genome-wide dis … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02577-1 Curvenote creates interactive publications based on digital-coding notebooks and aims to increase the transparency and reproducibility of data science. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02562-8 Airway hillocks were identified in 2018. These barrier structures in the mammalian airway are composed of tightly interlocking flat cells that shield an underlying population of highly regenerative and speci … | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02376-8 Scientists hope the discovery will inspire more palaeontologists from southeast Asia to explore the region’s fossil history. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02469-4 Tasked with finding better ways to conduct, distribute and fund research, the unit could set the standard for government-led ‘science of science’ initiatives. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02536-w Scientists are using consumer-genomics databases to link living people to ancestors from the recent and not-so-recent past. But the meaning of these connections isn’t always clear. | Continue reading
Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02531-1 The Step Pyramid of Djoser is accompanied by a dam-like structure and a moat. | Continue reading
Nature, Published online: 06 August 2024; doi:10.1038/d41586-024-02534-y The country can tackle its energy crisis by diversifying its energy sources, using storage systems and continually optimizing its grid. | Continue reading
Nature, Published online: 06 August 2024; doi:10.1038/d41586-024-02548-6 Fossil humerus offers clues about the rapid evolution of remote-island ‘hobbit’ species Homo floresiensis. | Continue reading
Nature, Published online: 06 August 2024; doi:10.1038/d41586-024-02533-z The option to attend meetings remotely provides career benefits to parents, carers, people with disabilities and others facing barriers to travel. | Continue reading
Nature, Published online: 06 August 2024; doi:10.1038/d41586-024-02537-9 An insider’s story of the discoveries that revealed the dazzling abilities of RNA, and the therapeutic possibilities that emerged. | Continue reading