FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions

Nature, Published online: 31 July 2024; doi:10.1038/s41586-024-07770-w FANCD2–FANCI is a sliding clamp that diffuses on double-stranded DNA but stalls when it reaches a single-stranded gap, providing a unified molecular mechanism that reconciles the roles of FANCD2–FANCI in the r … | Continue reading


@nature.com | 3 months ago

Histone serotonylation regulates ependymoma tumorigenesis

Nature, Published online: 31 July 2024; doi:10.1038/s41586-024-07751-z Serotonin has a role in ependymoma tumorigenesis through modifying histones and thereby regulating key transcription factors and activating specific oncogenic transcriptional networks in brain cells. | Continue reading


@nature.com | 3 months ago

Dopamine biases decisions by limiting temporal integration

Nature, Published online: 31 July 2024; doi:10.1038/s41586-024-07749-7 In Drosophila, dopamine sets motivational state during mating by regulating the integration of competing drives in copulation decision neurons, potentially indicative of a more general role for control over ne … | Continue reading


@nature.com | 3 months ago

The catalytic asymmetric polyene cyclization of homofarnesol to ambrox

Nature, Published online: 31 July 2024; doi:10.1038/s41586-024-07757-7 The catalytic asymmetric polyene cyclization of homofarnesol to ambrox is achieved using a highly Brønsted-acidic and confined imidodiphosphorimidate catalyst. | Continue reading


@nature.com | 3 months ago

Fish can tell the direction of sounds — here’s how

Nature, Published online: 31 July 2024; doi:10.1038/d41586-024-02518-y New research finally unravels the mystery of how fish can hear directionally. | Continue reading


@nature.com | 3 months ago

A joint bacterial effort to produce vitamin B12

Nature, Published online: 31 July 2024; doi:10.1038/d41586-024-02474-7 Vitamin B12 consists of two molecular components and has been thought to be synthesized only in full by certain bacteria. It emerges that two bacterial strains that each exclusively produce one building block … | Continue reading


@nature.com | 3 months ago

How pregnancy transforms the brain to prepare it for parenthood

Nature, Published online: 31 July 2024; doi:10.1038/d41586-024-02447-w It’s a transformational time long neglected by neuroscience. That is starting to change. | Continue reading


@nature.com | 3 months ago

Last men standing

Nature, Published online: 31 July 2024; doi:10.1038/d41586-024-02451-0 Double trouble. | Continue reading


@nature.com | 3 months ago

‘Ocean ranching’ has led to a pink salmon boom — but there might be a catch

Nature, Published online: 31 July 2024; doi:10.1038/d41586-024-02483-6 Unintended interbreeding between hatchery-bred and wild-born pink salmon could reduce resiliency of fish stocks. | Continue reading


@nature.com | 3 months ago

Supreme Court ruling alters risk landscape

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02495-2 Supreme Court ruling alters risk landscape | Continue reading


@nature.com | 3 months ago

Wasted renewables deny households cheap energy

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02497-0 Wasted renewables deny households cheap energy | Continue reading


@nature.com | 3 months ago

Polar bear threat for Arctic researchers

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02496-1 Polar bear threat for Arctic researchers | Continue reading


@nature.com | 3 months ago

Charged-up butterflies draw pollen through the air

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02491-6 Moths also accumulate static charge during flight that allows them to harvest pollen from flowers several millimetres away. | Continue reading


@nature.com | 3 months ago

Predatory conferences are on the rise. Here are five ways to tackle them

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02445-y Early-career researchers are being targeted by organizers of exploitative meetings. There needs to be more awareness and perhaps legal redress over this dangerous development. | Continue reading


@nature.com | 3 months ago

How to spot a predatory conference, and what science needs to do about them: a guide

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02360-2 Researchers who have fallen prey to predatory conferences share the tell-tale signs of a dud event. | Continue reading


@nature.com | 3 months ago

AI is complicating plagiarism. How should scientists respond?

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02371-z The explosive uptake of generative artificial intelligence in writing is raising difficult questions about when use of the technology should be allowed. | Continue reading


@nature.com | 3 months ago

Rhapsodies in green: the poetry of plant biology

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02442-1 Poems that bring plant biology to life, and remembering the achievements of the physicist Patrick Blackett, in our weekly dip into Nature’s archive. | Continue reading


@nature.com | 3 months ago

Guidelines on lab-grown embryo models are strong enough to meet ethical standards — and will build trust science

Nature, Published online: 30 July 2024; doi:10.1038/d41586-024-02446-x The UK code of practice for researchers working with stem-cell-based embryo models is designed to both reassure the public and provide valuable guidance to researchers. | Continue reading


@nature.com | 3 months ago

Mental maps help monkeys to navigate without sensory input

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02471-w Cognitive maps are internal representations of the external environment. Evidence from monkeys shows that a cognitive map can support the mental navigation of an array of landmarks without sensory input. | Continue reading


@nature.com | 3 months ago

Stop just paying lip service on publication integrity

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02449-8 Too often, journal assessments of potentially unreliable research are superficial, opaque and prolonged. Changes to the guidance given by the Committee on Publication Ethics could tighten up the process. | Continue reading


@nature.com | 3 months ago

Are our rock-climbing shoes shedding plastics?

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02450-1 Environmental scientist Anya Sherman studies how microplastics can be taken up by crops and people. | Continue reading


@nature.com | 3 months ago

Spectroscopic confirmation of two luminous galaxies at a redshift of 14

Nature, Published online: 29 July 2024; doi:10.1038/s41586-024-07860-9 Spectroscopic confirmation of two luminous galaxies at a redshift of 14 | Continue reading


@nature.com | 3 months ago

Lipids act as structural components of the pore of an ion-channel family

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02477-4 Structural, functional and computational evidence demonstrates that when certain ion channels are activated by mechanical force, they assume an open configuration in which the pore is formed by both protein an … | Continue reading


@nature.com | 3 months ago

Sexual harassment in science: biologists in India speak out

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02400-x Nature interviewed 12 female wildlife researchers who say they were harassed while working at conservation organizations in India. Why does the country’s sexual-harassment law sometimes fail to safeguard women … | Continue reading


@nature.com | 3 months ago

Blocking an inflammatory protein slows the pace of ageing

Nature, Published online: 29 July 2024; doi:10.1038/d41586-024-02300-0 Mice live longer and healthier lives when a cytokine protein called IL-11 is inhibited. The findings show how researchers can move beyond broad generalizations to engage with the nuances that modulate the pace … | Continue reading


@nature.com | 3 months ago

Daily briefing: Could these ‘leopard spots’ hint at ancient life on Mars?

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02499-y Tiny spots discovered in a rock on Mars could be signs of microbes that once lived on the red planet. Plus: The brain cells that encode the mother–baby bond in mice and how AI is changing the Olympics. | Continue reading


@nature.com | 3 months ago

Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus

Nature, Published online: 26 July 2024; doi:10.1038/s41586-024-07845-8 Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus | Continue reading


@nature.com | 3 months ago

Retraction notices are getting clearer — but progress is slow

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02423-4 Communications relating to retractions are often still opaque and lacking in detail, but an analysis finds some evidence of improvement. | Continue reading


@nature.com | 3 months ago

Effort to ‘Trump-proof’ US science grows, but will it succeed?

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02484-5 Unions are joining the Biden administration’s campaign to promote scientific integrity and protect government scientists from political interference. | Continue reading


@nature.com | 3 months ago

Strokes can damage the heart — but reining in the immune system might help

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02426-1 Heart injury is reduced in mice when the cells that trigger inflammation are blocked. | Continue reading


@nature.com | 3 months ago

How the rose got its iconic fragrance

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02424-3 A bouquet of genes involved in making volatile compounds helps to produce the flower’s characteristic scent. | Continue reading


@nature.com | 3 months ago

Meet the retired scientists who collaborate with younger colleagues

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02482-7 Julie Gould learns that age is no barrier to enjoying interesting work and life opportunities in retirement. | Continue reading


@nature.com | 3 months ago

Seventh patient ‘cured’ of HIV: why scientists are excited

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02463-w A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus. | Continue reading


@nature.com | 3 months ago

We are junior scientists from emerging economies — the world needs more researchers like us solving global problems

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02485-4 Scientific advancement relies on equitable international collaboration. And right now, it’s not equitable enough. | Continue reading


@nature.com | 3 months ago

Genetic links found to the world's biggest killer of new mothers

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02466-7 Genes associated with postpartum haemorrhage spotlight a hormone’s role in dangerous bleeding after childbirth. | Continue reading


@nature.com | 3 months ago

Elusive high-energy neutrinos spotted at LHC

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02465-8 Observations of electron neutrinos could allow physicists to test theories about the particles’ behaviour. | Continue reading


@nature.com | 3 months ago

Audio long read: Hope, despair and CRISPR — the race to save one woman’s life

Nature, Published online: 26 July 2024; doi:10.1038/d41586-024-02480-9 The tragic quest to develop a gene-editing therapy for a rare neurodegenerative disease showcases the messy state of modern drug development. | Continue reading


@nature.com | 3 months ago

Three ways AI is changing the 2024 Olympics for athletes and fans

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02427-0 From training to broadcasting, artificial intelligence will have an imprint on this year’s event for the first time. | Continue reading


@nature.com | 3 months ago

These brain cells help days-old mice to bond with mum

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02470-x Scientists pinpoint neurons that encode the mother–baby bond in the brains of infant mice. | Continue reading


@nature.com | 3 months ago

India budget: Modi bets big on nuclear energy and space

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02370-0 The government has focused on areas of national pride and applied science, as many researchers expected. | Continue reading


@nature.com | 3 months ago

AI is vulnerable to attack. Can it ever be used safely?

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02419-0 The models that underpin artificial-intelligence systems such as ChatGPT can be subject to attacks that elicit harmful behaviour. Making them safe will not be easy. | Continue reading


@nature.com | 3 months ago

Daily briefing: AI fed on a diet of AI-generated data spews nonsense

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02490-7 Training successive versions of AI models on text generated by the previous iteration quickly leads to the system producing gibberish. Plus, memory for music doesn’t fade with age and how placebos ease pain in … | Continue reading


@nature.com | 3 months ago

DeepMind hits milestone in solving maths problems — AI’s next grand challenge

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02441-2 AlphaProof showed its prowess on questions from this year’s Mathematical Olympiad — a step in the race to create substantial proofs with artificial intelligence. | Continue reading


@nature.com | 3 months ago

V. Craig Jordan obituary: pharmacologist who revolutionized breast cancer treatments

Nature, Published online: 25 July 2024; doi:10.1038/d41586-024-02448-9 Pioneer of targeted therapy in cancer who turned failed contraceptive tamoxifen into an essential drug for treating breast cancer and osteoporosis. | Continue reading


@nature.com | 3 months ago

Publisher Correction: Tautomeric mixture coordination enables efficient lead-free perovskite LEDs

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07844-9 Publisher Correction: Tautomeric mixture coordination enables efficient lead-free perovskite LEDs | Continue reading


@nature.com | 3 months ago

Carbon pricing reduces emissions

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02293-w A meta-analysis of 21 carbon-pricing schemes suggests that the strategy reduces greenhouse-gas emissions. Deciding how high to set prices is the next step — and one that might benefit from the insights of less … | Continue reading


@nature.com | 3 months ago

AI models fed AI-generated data quickly spew nonsense

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02420-7 Researchers gave successive versions of a large language model information produced by previous generations of the AI — and observed rapid collapse. | Continue reading


@nature.com | 3 months ago

SMYD5 methylation of rpL40 links ribosomal output to gastric cancer

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07718-0 The lysine methyltransferase SMYD5 and its newly identified substrate ribosomal protein L40 are implicated in the progression of gastric adenocarcinoma, and ablation of SMYD5 prevents metastatic disease in mou … | Continue reading


@nature.com | 3 months ago