TMEFF1 is a neuron-specific restriction factor for herpes simplex virus

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07670-z A study identifies TMEFF1 as a neuron-specific restriction factor essential for prevention of replication of herpes simplex virus type 1 in the central nervous system. | Continue reading


@nature.com | 3 months ago

In vivo interaction screening reveals liver-derived constraints to metastasis

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07715-3 Interactions between plexin B2 on hepatocytes and sempahorins on disseminated tumour cells regulate metastatic seeding in the liver. | Continue reading


@nature.com | 3 months ago

peri-Fused polyaromatic molecular contacts for perovskite solar cells

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07712-6 A peri-fused polyaromatic core structure is used to produce a relatively chemically inert and structurally rigid molecular contact that improves the efficiency and durability of perovskite solar cells. | Continue reading


@nature.com | 3 months ago

Global atmospheric methane uptake by upland tree woody surfaces

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07592-w Studies of in situ woody surface methane exchange in upland tropical, temperate and boreal forest trees find that methane uptake can result in a net tree methane sink that is globally significant and demonstra … | Continue reading


@nature.com | 3 months ago

Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07752-y Type 1 regulatory T cells (Tr1) represent a major obstacle that compromises naturally occurring and therapeutically induced tumour-specific immunity. | Continue reading


@nature.com | 3 months ago

Multi-heterojunctioned plastics with high thermoelectric figure of merit

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07724-2 Thermoelectric plastics with a high figure of merit, suppressed thermal conductivity and an enhanced power factor are realized by combining layered and bulk heterojunctions to create a polymeric multi-heteroju … | Continue reading


@nature.com | 3 months ago

Single-cell multiregion dissection of Alzheimer’s disease

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07606-7 A regional atlas of the ageing human brain—spanning six distinct anatomical regions from individuals with and without Alzheimer’s dementia—provides insights into cellular vulnerability, response and resilience … | Continue reading


@nature.com | 3 months ago

Human TMEFF1 is a restriction factor for herpes simplex virus in the brain

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07745-x A study of two childhood cases of herpes simplex encephalitis shows that TMEFF1 interacts with the HSV-1 cell-surface receptor NECTIN-1, preventing HSV-1 from fusing with the cell membrane and entering cortica … | Continue reading


@nature.com | 3 months ago

Shifts in receptors during submergence of an encephalitic arbovirus

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07740-2 Knockout studies using CRISPR–Cas9 identify PCDH10 as a selective host cellular receptor for western equine encephalitis virus. | Continue reading


@nature.com | 3 months ago

Molecular basis of human noradrenaline transporter reuptake and inhibition

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07719-z The cryo-electron microscopy structures of the human noradrenaline transporter in both the apo state and bound to substrates or antidepressant drugs are resolved. | Continue reading


@nature.com | 3 months ago

Jurassic fossil juvenile reveals prolonged life history in early mammals

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07733-1 Juvenile and adult skeletons of Middle Jurassic Krusatodon from the Isle of Skye, Scotland, show that this mouse-sized mammaliaform had longer development and lifespan than modern mammals of similar mass. | Continue reading


@nature.com | 3 months ago

Global net climate effects of anthropogenic reactive nitrogen

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07714-4 A comprehensive model framework is used to estimate the global net direct radiative forcing of anthropogenic reactive nitrogen as being about −0.34 W m−2, which has a cooling effect on the climate. | Continue reading


@nature.com | 3 months ago

Deep, hot, ancient melting recorded by ultralow oxygen fugacity in peridotites

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07603-w Analysis of peridotites reveals ultralow oxygen fugacity, suggesting that rafts of ancient, ultrareduced mantle were generated by deep melting at high temperatures and continue to circulate in the modern mantl … | Continue reading


@nature.com | 3 months ago

Cultivation and visualization of a methanogen of the phylum Thermoproteota

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07631-6 We demonstrate that the ability to conserve energy coupled to methane production is not restricted to the Euryarchaeota and is much more widespread than originally thought. | Continue reading


@nature.com | 3 months ago

Isolation of a methyl-reducing methanogen outside the Euryarchaeota

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07728-y Methanosuratincola petrocarbonis LWZ-6 is a strict hydrogen-dependent methylotrophic methanogen that does not ferment sugars, peptides or amino acids. | Continue reading


@nature.com | 3 months ago

A human autoimmune organoid model reveals IL-7 function in coeliac disease

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07716-2 A human in vitro model of coeliac disease comprising duodenal organoids that maintain both epithelium and an immune microenvironment finds a previously unsuspected role for IL-7 in gluten-induced epithelial de … | Continue reading


@nature.com | 3 months ago

Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07720-6 Cryo-electron microscopy, in vitro reconstitution and molecular dynamics simulations provide insight into the architecture of a plasma membrane microdomain in yeast, the organization and dynamics of the membra … | Continue reading


@nature.com | 3 months ago

Blood culture-free ultra-rapid antimicrobial susceptibility testing

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07725-1 An ultra-rapid antimicrobial susceptibility testing method is introduced that bypasses the need for traditional blood culture, demonstrating the potential to significantly reduce the turnaround time of reporti … | Continue reading


@nature.com | 3 months ago

AI models collapse when trained on recursively generated data

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07566-y Analysis shows that indiscriminately training generative artificial intelligence on real and generated content, usually done by scraping data from the Internet, can lead to a collapse in the ability of the mod … | Continue reading


@nature.com | 3 months ago

Rapid sepsis test identifies bacteria that spark life-threatening infection

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02462-x New method can help guide treatment with most effective antibiotic — plus how things get weird when an AI is trained on AI-created text. | Continue reading


@nature.com | 3 months ago

So you got a null result. Will anyone publish it?

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02383-9 Researchers have tried a bunch of strategies to get more negative results into the literature. Nature asks whether they are working. | Continue reading


@nature.com | 3 months ago

Motor neurons move a fly’s head in different directions depending on its starting posture

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02401-w Motor neurons control the muscles and are therefore the only means through which the brain can move the body and interact with the world. The finding that motor neurons move a fly’s body differently depending … | Continue reading


@nature.com | 3 months ago

Every part of you

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02388-4 How to be happy? | Continue reading


@nature.com | 3 months ago

How do placebos ease pain? Mouse brain study offers clues

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02439-w The discovery of a brain circuit involved in the pain-relieving effect of placebos could lead to new treatments. | Continue reading


@nature.com | 3 months ago

Memory for music doesn’t diminish with age

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02369-7 Eighty-year-olds are able to identify familiar tunes just as well as teenagers can. | Continue reading


@nature.com | 3 months ago

Why you should perform a premortem on your research

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02344-2 Carsten Lund Pedersen introduces a tool for improving the success rate of your papers, projects and partnerships. | Continue reading


@nature.com | 3 months ago

The ape Y chromosome evolves extremely rapidly, but the X chromosome is conserved

Nature, Published online: 24 July 2024; doi:10.1038/d41586-024-02404-7 The ape sex chromosomes have now been fully sequenced. Rapid evolution has led to extreme differences in the Y chromosome between species, whereas the X chromosome experienced much less dynamic changes. The pa … | Continue reading


@nature.com | 3 months ago

Methyl-reducing methanogenesis by a thermophilic culture of Korarchaeia

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07829-8 Methyl-reducing methanogenesis by a thermophilic culture of Korarchaeia | Continue reading


@nature.com | 3 months ago

Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle

Nature, Published online: 25 July 2024; doi:10.1038/s41586-024-07849-4 Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle | Continue reading


@nature.com | 3 months ago

Google AI predicts long-term climate trends and weather — in minutes

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02391-9 Models that are more reliable and less energy-intensive could help us to better prepare for extreme weather. | Continue reading


@nature.com | 3 months ago

Boost French research by increasing freedom for scientists and universities

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02382-w The new French government should support education and research by improving budgets. | Continue reading


@nature.com | 3 months ago

Publisher Correction: Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling

Nature, Published online: 23 July 2024; doi:10.1038/s41586-024-07847-6 Publisher Correction: Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling | Continue reading


@nature.com | 3 months ago

Daily briefing: Where US presidential contender Kamala Harris stands on science

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02428-z The US vice-president has stood up for maternal health issues and for improving the diversity of the scientific workforce. Plus, a mysterious source of ‘dark oxygen’ discovered on the sea floor. | Continue reading


@nature.com | 3 months ago

AI & robotics briefing: Digital primordial soup creates ‘computational life’

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02431-4 Self-replicating programs can emerge from a random soup of tens of thousands of pieces of computer code. Plus, how astronomers unmask deepfakes and did AlphaFold really solve protein folding? | Continue reading


@nature.com | 3 months ago

Hijacked journals are still a threat — here’s what publishers can do about them

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02399-1 A long-standing problem that affects publishers and authors alike, journal hijacking can damage reputations and steal article-processing fees. | Continue reading


@nature.com | 3 months ago

Monitor soil health using advanced technologies

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02396-4 Monitor soil health using advanced technologies | Continue reading


@nature.com | 3 months ago

Cement at 200: towards net-zero fully recycled concrete

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02395-5 Cement at 200: towards net-zero fully recycled concrete | Continue reading


@nature.com | 3 months ago

Hungarian researchers struggle amid EU funding ban

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02397-3 Hungarian researchers struggle amid EU funding ban | Continue reading


@nature.com | 3 months ago

Why US–China relations are too important to be left to politicians

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02385-7 In an age of geopolitical tensions, researchers need to be realistic and think beyond fundamental science to chart a safe path for collaboration. | Continue reading


@nature.com | 3 months ago

A stroke derailed my academic career. Now I’m getting back on track

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02413-6 A brain haemorrhage late in pregnancy upended Parisa Hosseinzadeh’s life — and her tenure clock. Thanks to supportive physicians, family and colleagues, she’s restarting her academic career. | Continue reading


@nature.com | 3 months ago

Discovery of oxygen commemorated at Joseph Priestley’s grave

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02231-w Centennial celebrations mark the discovery of oxygen, and a physicist shares ideas about why the pyramids were built, in our weekly dip into Nature’s archive. | Continue reading


@nature.com | 3 months ago

Heaviest element yet within reach after major breakthrough

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02416-3 Success with a new route to producing superheavy elements paves the way to making the elusive element 120. | Continue reading


@nature.com | 3 months ago

Inflammation averted by adhesive coating on implants

Nature, Published online: 23 July 2024; doi:10.1038/d41586-024-02348-y Coating implants with an adhesive layer that bonds them to target tissue can prevent the formation of observable fibrous capsules on various organs and tissues, including the abdominal wall, colon, stomach, lu … | Continue reading


@nature.com | 3 months ago

Neural circuit basis of placebo pain relief

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07816-z Neural circuit basis of placebo pain relief | Continue reading


@nature.com | 3 months ago

A temperate super-Jupiter imaged with JWST in the mid-infrared

Nature, Published online: 24 July 2024; doi:10.1038/s41586-024-07837-8 A temperate super-Jupiter imaged with JWST in the mid-infrared | Continue reading


@nature.com | 3 months ago

What Kamala Harris’s historic bid for the US presidency means for science

Nature, Published online: 22 July 2024; doi:10.1038/d41586-024-02394-6 The daughter of a scientist and a supporter of diversity in STEM, Harris’s prospects have stirred optimism among scientists. | Continue reading


@nature.com | 3 months ago

A dumpster full of mercury and other things to avoid: lab closures made simple

Nature, Published online: 22 July 2024; doi:10.1038/d41586-024-02372-y Julie Gould hears about the practicalities of shutting down or handing over a lab as retirement looms. | Continue reading


@nature.com | 3 months ago

I’ve built a career without a big golden grant. Here’s how

Nature, Published online: 22 July 2024; doi:10.1038/d41586-024-02390-w NIH funding is the goal for many US health researchers, but you can be successful in academia without it, says Brandon Brown. | Continue reading


@nature.com | 3 months ago