Light turns tiny crystals into force sensors

Nature, Published online: 01 January 2025; doi:10.1038/d41586-024-04103-9 Two studies show that the light emitted by nanocrystals embedded with luminescent ions can be used to sense forces with high spatial resolution — even when those forces are inside a microscopic living worm. | Continue reading


@nature.com | 14 days ago

Sleep microstructure organizes memory replay

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08340-w The temporal microstructure of the brain can multiplex distinct cognitive processes during sleep to support continuous learning. | Continue reading


@nature.com | 14 days ago

The progression of basaltic–rhyolitic melt storage at Yellowstone Caldera

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08286-z The resistivity structure of Yellowstone Caldera’s crustal magma reservoir indicates that the magma reservoirs are not eruptible at present and that the locus of future volcanism has shifted to northeast Ye … | Continue reading


@nature.com | 14 days ago

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08319-7 An Arabidopsis long terminal repeat retrotransposon integrates de novo into regions occupied by centromere-specific histone variant, showing the impact of centromeric chromatin on transposable element-media … | Continue reading


@nature.com | 14 days ago

Aspartate signalling drives lung metastasis via alternative translation

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08335-7 Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis. | Continue reading


@nature.com | 14 days ago

Learning the fitness dynamics of pathogens from phylogenies

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08309-9 Phylowave, an innovative phylogenetic approach, can identify the main circulating pathogen lineages with increased fitness and the associated genetic changes, enabling the timely identification of emergent … | Continue reading


@nature.com | 14 days ago

A pulsar-like polarization angle swing from a nearby fast radio burst

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08184-4 FRB 20221022A, detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst project, shows a pronounced change in polarization during the burst, providing important clues into the nature … | Continue reading


@nature.com | 14 days ago

Abrupt changes in biomass burning during the last glacial period

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08363-3 An increase in wildfire extent and related greenhouse gas emissions can be linked to abrupt climatic changes during the last glacial period. | Continue reading


@nature.com | 14 days ago

Gliomagenesis mimics an injury response orchestrated by neural crest-like cells

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08356-2 A study using glioblastoma mouse models, serial magnetic resonance imaging and single-cell profiling details changes in the identity and balance of cellular states from initiation of tumorigenesis to the en … | Continue reading


@nature.com | 14 days ago

Structural diversity of axonemes across mammalian motile cilia

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08337-5 Cryoelectron microscopy, cryoelectron tomography and proteomics are used to resolve the 96-nm modular repeat of axonemal doublet microtubules from both sperm flagella and epithelial cilia of the oviduct, br … | Continue reading


@nature.com | 14 days ago

Magnetospheric origin of a fast radio burst constrained using scintillation

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08297-w The detection of scintillation caused by inhomogeneous plasma near a fast radio burst indicates an emission process that occurs within or just beyond the magnetosphere of a compact object. | Continue reading


@nature.com | 14 days ago

Diversity and biogeography of the bacterial microbiome in glacier-fed streams

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08313-z Leveraging metabarcoding and metagenomics, a survey of bacteria in the benthic microbiome across 152 glacier-fed streams (GFSs) provides a global reference for future climate-change microbiology studies on … | Continue reading


@nature.com | 14 days ago

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08341-9 Cellular, transcriptomic and proteomic analyses of organoids derived from human induced pluripotent stem cells show that mTOR pathway hypoactivation is involved in two genetically distinct lissencephaly spe … | Continue reading


@nature.com | 14 days ago

Infrared nanosensors of piconewton to micronewton forces

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08221-2 An avalanching-nanoparticle force sensor that can operate in the piconewton-to-micronewton range with exceptional force responsiveness is achieved by using the mechanical sensitivity of the photon-avalanchi … | Continue reading


@nature.com | 14 days ago

Monoallelic expression can govern penetrance of inborn errors of immunity

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08346-4 Somatically determined preferential allelic expression of select genes that when mutated cause inborn errors of immunity corresponds with disease phenotypes, suggesting that the penetrance and expressivity … | Continue reading


@nature.com | 14 days ago

Formation of individual stripes in a mixed-dimensional cold-atom Fermi–Hubbard system

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08270-7 Observations of the formation of individual stripes in a mixed-dimensional cold-atom Fermi–Hubbard quantum simulator are described, enhancing understanding of the phase diagram of high-temperature supercond … | Continue reading


@nature.com | 14 days ago

Non-Abelian lattice gauge fields in photonic synthetic frequency dimensions

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08259-2 Non-Abelian lattice gauge fields in photonic synthetic frequency dimensions can be used to study lattice physics in a scalable and programmable way. | Continue reading


@nature.com | 14 days ago

Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08350-8 A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional changes an … | Continue reading


@nature.com | 14 days ago

A collicular map for touch-guided tongue control

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08339-3 Touch-guided tongue control in mice relies on a collicular mechanosensorimotor map, analogous to collicular visuomotor maps associated with visually guided orienting across many species. | Continue reading


@nature.com | 14 days ago

High-resolution genomic history of early medieval Europe

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08275-2 Twigstats, a method for ancestry reconstruction, provides high-resolution genetic histories and movement patterns of people living in Europe during the first millennium ce. | Continue reading


@nature.com | 14 days ago

FBP1 controls liver cancer evolution from senescent MASH hepatocytes

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08317-9 The p53 target FBP1 is elevated in senescent-like metabolic-dysfunction-associated steatohepatitis hepatocytes but suppressed through promoter hypermethylation and proteasomal degradation in most human hepa … | Continue reading


@nature.com | 14 days ago

Upconverting microgauges reveal intraluminal force dynamics in vivo

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08331-x Nanoparticle-based ‘microgauges’ are developed for in vivo force sensing and deployed in C. elegans to investigate how mechanical force correlates with electrical signalling in neuromuscular organs. | Continue reading


@nature.com | 14 days ago

Bone marrow niches orchestrate stem-cell hierarchy and immune tolerance

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08352-6 Previously undescribed hierarchical arrangements in haematopoietic stem cells and their niches that mediate both regenerative potential and immune privilege are identified. | Continue reading


@nature.com | 14 days ago

GaAs nano-ridge laser diodes fully fabricated in a 300-mm CMOS pilot line

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08364-2 A new integration approach, nano-ridge engineering, enables electrically driven GaAs-based laser diodes to be fabricated on Si wafers in a complementary metal–oxide–semiconductor (CMOS) pilot line, showing … | Continue reading


@nature.com | 14 days ago

Limitations of ice cores in reconstructing temperature seasonality

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08181-7 Limitations of ice cores in reconstructing temperature seasonality | Continue reading


@nature.com | 14 days ago

Reply to: Limitations of ice cores in reconstructing temperature seasonality

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08182-6 Reply to: Limitations of ice cores in reconstructing temperature seasonality | Continue reading


@nature.com | 14 days ago

Countdown to a nuclear clock: a three minute guide

Nature, Published online: 31 December 2024; doi:10.1038/d41586-024-04209-0 A long-sought nuclear clock is closer than ever thanks to ultra-accurate measurements of Thorium-229. | Continue reading


@nature.com | 15 days ago

How AI is unlocking ancient texts — and could rewrite history

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04161-z From deciphering burnt Roman scrolls to reading crumbling cuneiform tablets, neural networks could give researchers more data than they’ve had in centuries. | Continue reading


@nature.com | 16 days ago

Apply the legal ‘true malice’ principle to protect research-misconduct sleuths

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04230-3 Apply the legal ‘true malice’ principle to protect research-misconduct sleuths | Continue reading


@nature.com | 16 days ago

To solve the global wildfire crisis, don’t just focus on flames

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04228-x To solve the global wildfire crisis, don’t just focus on flames | Continue reading


@nature.com | 16 days ago

One way to find mental-health support when professional help is not available

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04231-2 One way to find mental-health support when professional help is not available | Continue reading


@nature.com | 16 days ago

Chinese rice actually tastes ever more nice

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04229-w Chinese rice actually tastes ever more nice | Continue reading


@nature.com | 16 days ago

Of your own device

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04171-x A taste for freedom. | Continue reading


@nature.com | 16 days ago

2025 must be the year when the rules of global finance are reformed

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04159-7 The current international financial architecture is a key reason that the UN Sustainable Development Goals are failing. A landmark conference in Spain must make progress in reforming it. | Continue reading


@nature.com | 16 days ago

The case for Latin to communicate science

Nature, Published online: 30 December 2024; doi:10.1038/d41586-024-04122-6 The organization of bee society, and a suggestion that Latin be used as the international scientific language, in our weekly dip into Nature’s archive. | Continue reading


@nature.com | 16 days ago

Audio long read: How a silly science prize changed my career

Nature, Published online: 27 December 2024; doi:10.1038/d41586-024-03970-6 The Ig Nobel prizes are famed for their spotlighting of offbeat research. Nature investigates how some winners feel about their ‘honour’. | Continue reading


@nature.com | 19 days ago

The Nature Podcast highlights of 2024

Nature, Published online: 25 December 2024; doi:10.1038/d41586-024-03981-3 The team select some of their favourite stories from the past 12 months. | Continue reading


@nature.com | 21 days ago

'CAR T cells': a festive parody song from the Nature Podcast

Nature, Published online: 25 December 2024; doi:10.1038/d41586-024-04238-9 The Nature Podcast team have rewritten a popular holiday song in light of one of the biggest science trends of 2024. | Continue reading


@nature.com | 21 days ago

‘Ozempic, you’re able’: a festive parody song from the Nature Podcast

Nature, Published online: 24 December 2024; doi:10.1038/d41586-024-04239-8 The Nature Podcast team have rewritten a popular holiday song in light of one of the biggest science stories of 2024. | Continue reading


@nature.com | 22 days ago

Digital origins for ancient digits

Nature, Published online: 23 December 2024; doi:10.1038/d41586-024-04123-5 Pupil contractions in a talking parrot, and how ancient numerals were derived from counting on fingers, in our weekly dip into Nature’s archive. | Continue reading


@nature.com | 23 days ago

Author Correction: π-HuB: the proteomic navigator of the human body

Nature, Published online: 23 December 2024; doi:10.1038/s41586-024-08555-x Author Correction: π-HuB: the proteomic navigator of the human body | Continue reading


@nature.com | 23 days ago

Steering perovskite precursor solutions for multijunction photovoltaics

Nature, Published online: 23 December 2024; doi:10.1038/s41586-024-08546-y Steering perovskite precursor solutions for multijunction photovoltaics | Continue reading


@nature.com | 23 days ago

Total synthesis of twenty-five picrotoxanes by virtual library selection

Nature, Published online: 23 December 2024; doi:10.1038/s41586-024-08538-y Total synthesis of twenty-five picrotoxanes by virtual library selection | Continue reading


@nature.com | 23 days ago

Stem cells head to the clinic: treatments for cancer, diabetes and Parkinson’s disease could soon be here

Nature, Published online: 20 December 2024; doi:10.1038/d41586-024-04160-0 More than 100 clinical trials put stem cells for regenerative medicine to the test. It’s a turning point for a field beset with ethical and political controversy. | Continue reading


@nature.com | 26 days ago

Build your own receptor: modular system can be tailored to any antigen

Nature, Published online: 20 December 2024; doi:10.1038/d41586-024-04178-4 PAGERs provide modular, customizable G-protein-coupled receptors for cell-signalling studies. | Continue reading


@nature.com | 26 days ago

Can novelty scores on papers shift the power dynamics in scientific publishing?

Nature, Published online: 20 December 2024; doi:10.1038/d41586-024-04021-w By providing measures of novelty, DeSci Publish hopes to shift the bargaining power between journals and authors. | Continue reading


@nature.com | 26 days ago

Is political interference causing faculty brain drain in the southern United States?

Nature, Published online: 20 December 2024; doi:10.1038/d41586-024-04070-1 Faculty members say academic freedom is under fire, and many are seeking work outside the region. | Continue reading


@nature.com | 26 days ago

I create routes through trees to help stop howler monkeys being electrocuted by power lines

Nature, Published online: 20 December 2024; doi:10.1038/d41586-024-04170-y Inés Azofeifa Rojas monitors troop behaviour to maintain canopy connectivity. | Continue reading


@nature.com | 26 days ago