A virally encoded high-resolution screen of cytomegalovirus dependencies

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07503-z A genetic screen that expresses single guide RNA libraries targeting host genes in the human cytomegalovirus genome enables identification of host factors and provides insights into their roles during the vira … | Continue reading


@nature.com | 5 months ago

A disease-associated gene desert directs macrophage inflammation through ETS2

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07501-1 ETS2—which is associated with inflammatory bowel disease, ankylosing spondylitis, primary sclerosing cholangitis and Takayasu’s arteritis—is a central regulator of human inflammatory macrophages. | Continue reading


@nature.com | 5 months ago

Profiling phagosome proteins identifies PD-L1 as a fungal-binding receptor

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07499-6 Proximity labelling of phagosomal contents is used to identify proteins that localize to phagosomes in host–microorganism interactions. | Continue reading


@nature.com | 5 months ago

MYCT1 controls environmental sensing in human haematopoietic stem cells

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07478-x MYCT1 is identified as a crucial regulator of cellular properties essential for the stemness of human haematopoietic stem cells, a finding that may help improve successful in vitro expansion of these cells for … | Continue reading


@nature.com | 5 months ago

Observation of 2D-magnesium-intercalated gallium nitride superlattices

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07513-x The spontaneous formation of magnesium-intercalated gallium nitride superlattices by the interstitial intercalation of two-dimensional magnesium results in considerable compressive strain perpendicular to the … | Continue reading


@nature.com | 5 months ago

Fault-network geometry influences earthquake frictional behaviour

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07518-6 Analysis of some of the main fault zones in California shows that the presence of complex earthquake fault-network geometries results in geometric locking that promotes stick-slip behaviour, whereas simpler ge … | Continue reading


@nature.com | 5 months ago

Injectable ultrasonic sensor for wireless monitoring of intracranial signals

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07334-y A bioresorbable, wireless hydrogel (metagel) sensor, encompassing both biodegradable and stimulus-responsive hydrogels for ultrasonic monitoring of intracranial signals, was implanted into intracranial space w … | Continue reading


@nature.com | 5 months ago

A late-Ediacaran crown-group sponge animal

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07520-y Cross-hatch impressions from Ediacaran rocks in China are interpreted as having been left by a crown-group sponge fossil, Helicolocellus cantori gen. et sp. nov., characterized by an organic latticework skelet … | Continue reading


@nature.com | 5 months ago

Myelin plasticity in the ventral tegmental area is required for opioid reward

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07525-7 Oligodendrogenesis is shown to be involved in reward learning, with dopaminergic neuronal activity-regulated myelin plasticity being an important reward circuit modification. | Continue reading


@nature.com | 5 months ago

Misunderstanding the harms of online misinformation

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07417-w This Perspective identifies common misperceptions regarding the harms of online misinformation, finding that exposure to false and inflammatory content is rare and concentrated among a small minority of people … | Continue reading


@nature.com | 5 months ago

Early stages of covalent organic framework formation imaged in operando

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07483-0 The operando imaging of the early formation stages of covalent organic frameworks with the optical technique interferometric scattering microscopy leads to mechanistic insights, enabling the rational developme … | Continue reading


@nature.com | 5 months ago

Nuclear position and local acetyl-CoA production regulate chromatin state

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07471-4 Analyses of histone acetylation in Drosophila wing imaginal discs reveal distinct patterns of acetylation and cellular metabolism that affect gene expression and cell specification. | Continue reading


@nature.com | 5 months ago

The time between Palaeolithic hearths

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07467-0 High-resolution time differences between six Middle Palaeolithic hearths from El Salt Unit x (Spain) obtained through archaeomagnetic and archaeostratigraphic analyses show sometimes decade-long intervals betw … | Continue reading


@nature.com | 5 months ago

Senescent glia link mitochondrial dysfunction and lipid accumulation

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07516-8 The authors identify naturally occurring senescent glia in aged Drosophila brains and decipher their origin and influence, determining that they can appear in response to neuronal mitochondrial dysfunction and … | Continue reading


@nature.com | 5 months ago

Descending networks transform command signals into population motor control

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07523-9 Command-like descending neurons in Drosophila melanogaster recruit additional descending neuronal networks to co-ordinate behaviours that require multiple motor subroutines controlling numerous body parts. | Continue reading


@nature.com | 5 months ago

Large-area, self-healing block copolymer membranes for energy conversion

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07481-2 We introduce a self-assembly strategy that uses the interface of an aqueous two-phase system to template and stabilize molecularly thin biomimetic block copolymer bilayers of scalable area that can exceed 10 c … | Continue reading


@nature.com | 5 months ago

Scaling neural machine translation to 200 languages

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07335-x Scaling neural machine translation to 200 languages is achieved by No Language Left Behind, a single massively multilingual model that leverages transfer learning across languages. | Continue reading


@nature.com | 5 months ago

Global shortfalls in documented actions to conserve biodiversity

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07498-7 A global assessment of conservation interventions for threatened species across a range of data sources finds that interventions for most species remain insufficient or absent. | Continue reading


@nature.com | 5 months ago

Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07472-3 A study shows that epididymal spermatozoa are sensitive to preconception diet, identifies mitochondrial tRNAs and their fragments as sperm-borne factors and demonstrates epigenetic inheritance of mitochondrial … | Continue reading


@nature.com | 5 months ago

Microbial competition for phosphorus limits the CO2 response of a mature forest

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07491-0 Microbial pre-emption of mineralized soil P limits the capacity of trees for increased P uptake and assimilation under elevated CO2 and therefore restricts their capacity to sequester extra C. | Continue reading


@nature.com | 5 months ago

Capturing carbon dioxide from air with charged-sorbents

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07449-2 Charged-sorbents are a new class of designer sorbent materials for the capture of carbon dioxide from the atmosphere, and can be regenerated at low temperatures with direct heating generation using renewable e … | Continue reading


@nature.com | 5 months ago

Companies inadvertently fund online misinformation despite consumer backlash

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07404-1 Many companies unknowingly advertise on websites that publish misinformation despite the reputational and financial risks, and increased transparency for consumers and advertisers could counter unintended ad r … | Continue reading


@nature.com | 5 months ago

Single-cell nascent RNA sequencing unveils coordinated global transcription

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07517-7 Nascent transcription in genes and enhancers genome-wide at the single-cell level is quantified using global run-on and sequencing (GRO–seq) with click chemistry. | Continue reading


@nature.com | 5 months ago

Observation of edge states derived from topological helix chains

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07484-z Unusual electronic states derived from topological helix chains were observed that support the emergent bound states in elemental tellurium. | Continue reading


@nature.com | 5 months ago

Post-January 6th deplatforming reduced the reach of misinformation on Twitter

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07524-8 Difference-in-differences analysis indicates that the decision by Twitter to deplatform 70,000 users following the events at the US Capitol on 6 January 2021 had wider effects on the spread of misinformation. | Continue reading


@nature.com | 5 months ago

Visualization of oxygen vacancies and self-doped ligand holes in La3Ni2O7−δ

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07482-1 Direct visualization of oxygen vacancies and self-doped ligand holes reveals the role of ligand oxygen in La3Ni2O7−δ and provides further understanding of superconducting nickelate materials. | Continue reading


@nature.com | 5 months ago

China seeks global impact and recognition

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01595-3 The country’s lead in high-quality research looks set to shape the direction of world science. | Continue reading


@nature.com | 5 months ago

Chinese science still has room to grow

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01600-9 Strengths in chemistry and the physical sciences have propelled the country to the top of the Nature Index. But there is untapped potential in other subject areas. | Continue reading


@nature.com | 5 months ago

China’s big-science bet

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01597-1 With a view to increase its prestige and influence in global science, the country is investing heavily in major facilities. | Continue reading


@nature.com | 5 months ago

A guide to the Nature Index

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01601-8 A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com. | Continue reading


@nature.com | 5 months ago

Chinese research collaborations shift to the Belt and Road

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01598-0 Data from the Nature Index suggest changing make-up of international partnerships. | Continue reading


@nature.com | 5 months ago

China’s research clout leads to growth in homegrown science publishing

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01596-2 Self-reliance and a wish to set the agenda might explain concerted push to produce domestic journals. | Continue reading


@nature.com | 5 months ago

Why China has been a growing study destination for African students

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01599-z Scholarships and soft power among reasons for increasing numbers, but graduates return with mixed reviews. | Continue reading


@nature.com | 5 months ago

1,001 best hikes on Mars: The Peterson Historic Trail (‘Peterson’s folly’)

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01593-5 A walk into history. | Continue reading


@nature.com | 5 months ago

Author Correction: High-speed and large-scale intrinsically stretchable integrated circuits

Nature, Published online: 05 June 2024; doi:10.1038/s41586-024-07416-x Author Correction: High-speed and large-scale intrinsically stretchable integrated circuits | Continue reading


@nature.com | 5 months ago

‘I saw that discrimination wasn’t hearsay or rumours — it really did exist’

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01685-2 JoAnn Trejo attributes her path to pharmacology to her immigrant family’s strong work ethic. Today, she uses recruitment and mentorship training to unlock the potential of other scientists from under-represent … | Continue reading


@nature.com | 5 months ago

MDMA therapy for PTSD rejected by FDA panel

Nature, Published online: 05 June 2024; doi:10.1038/d41586-024-01622-3 Scientific advisors vote overwhelmingly that the risks of MDMA treatment for post-traumatic stress disorder outweigh the benefits. | Continue reading


@nature.com | 5 months ago

Daily briefing: Anthony Fauci denies ‘preposterous’ accusations of COVID origins cover-up

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01682-5 Fauci, the face of the US pandemic response, was in the hot-seat at a politically polarized hearing. Plus, the first rock samples collected from the far side of the Moon and how to overcome stage fright in lab … | Continue reading


@nature.com | 5 months ago

What Modi’s third term in India means for science

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01602-7 Research that drives development and national pride will take centre stage for the next five years, say researchers. | Continue reading


@nature.com | 5 months ago

Super-fast Microsoft AI is first to predict air pollution for the whole world

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01677-2 The model, called Aurora, also forecasts global weather for 10 days — all in less than a minute. | Continue reading


@nature.com | 5 months ago

Problem-solving PhD students are prepared for careers in industry

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01589-1 PhD programmes in an industrial setting were on the rise in the 1970s, and a reflection on Darwin’s rich accomplishments, in the weekly dip into Nature’s archive. | Continue reading


@nature.com | 5 months ago

Negotiating a pandemic treaty is just the first step — how will countries comply?

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01586-4 Governments must act now on vaccine and pathogen-sample sharing, or any agreement will be a promise only on paper. | Continue reading


@nature.com | 5 months ago

Accelerating AI: the cutting-edge chips powering the computing revolution

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01544-0 Engineers are harnessing the powers of graphics processing units (GPUs) and more, with a bevy of tricks to meet the computational demands of artificial intelligence. | Continue reading


@nature.com | 5 months ago

Author Correction: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

Nature, Published online: 04 June 2024; doi:10.1038/s41586-024-07594-8 Author Correction: Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates | Continue reading


@nature.com | 5 months ago

Mega engineering projects won’t stop a repeat of the devastating southern Brazil floods

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01665-6 Mega engineering projects won’t stop a repeat of the devastating southern Brazil floods | Continue reading


@nature.com | 5 months ago

Underfunding cannabis research hampers sensible policymaking and boosts the black market

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01668-3 Underfunding cannabis research hampers sensible policymaking and boosts the black market | Continue reading


@nature.com | 5 months ago

Neurotechnologies that can read our mind could undermine international norms on freedom of thought

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01666-5 Neurotechnologies that can read our mind could undermine international norms on freedom of thought | Continue reading


@nature.com | 5 months ago

Organic product legislation ignores agricultural plastic use — that must change

Nature, Published online: 04 June 2024; doi:10.1038/d41586-024-01667-4 Organic product legislation ignores agricultural plastic use — that must change | Continue reading


@nature.com | 5 months ago