United States sets the pace for implantable brain–computer interfaces

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03046-5 As development of the technology accelerates, countries are weighing the costs and benefits of how they regulate it. | Continue reading


@nature.com | 1 month ago

A guide to the Nature Index

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03050-9 A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com. | Continue reading


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See a tardigrade ride a worm in the world’s weirdest rodeo — September’s best science images

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03153-3 The month’s sharpest science shots — selected by Nature’s photo team. | Continue reading


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Neurotechnology race ramps up, but fundamental questions remain

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03043-8 The United States is setting the pace, but other nations are following their own paths. | Continue reading


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The global imbalance of neurological conditions

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03048-3 Neurological conditions affect more than 40% of the population, and some countries are struggling to cope. | Continue reading


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High-performers and specialists in neuroscience research

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03045-6 An overview of the countries and institutions that dedicate a high proportion of their research to neuroscience. | Continue reading


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A complete wiring diagram of the fruit-fly brain

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03029-6 Neuroscientists have reconstructed the first complete wiring map of the fruit-fly brain, including 140,000 neurons and more than 50 million connections. This resource has already begun to revolutionize the … | Continue reading


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Hybrid protein filaments are a surprise twist in neurodegeneration

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03054-5 Abnormal filaments of a single type of protein are hallmarks of neurodegeneration. Structural studies reveal filaments made from two discrete but interwoven proteins, giving clues about the origin of neurod … | Continue reading


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Inducing novel endosymbioses by implanting bacteria in fungi

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-08010-x A study presents an approach to establish and track a new endosymbiotic partnership by implanting bacteria in a non-host fungus and shows that stable inheritance of the implanted bacteria is possible with p … | Continue reading


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CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07972-2 CRISPR–Cas9 screens in cultures of young and old neural stem cells (NSCs) and in vivo in old mice identify gene knockouts that can boost old NSC activation and neurogenesis, with Slc2a4, which encodes the g … | Continue reading


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Neural circuit mechanisms underlying context-specific halting in Drosophila

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07854-7 Two halting mechanisms, ‘walk-OFF’ and ‘brake’, are shown to be engaged by distinct neural circuits in Drosophila, in a context dependent manner. | Continue reading


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Predicting visual function by interpreting a neuronal wiring diagram

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07953-5 A study demonstrates the interpretation of a neuronal wiring diagram of the optic lobe of Drosophila, yielding theoretical predictions about visual functions of this structure. | Continue reading


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Calcium-permeable AMPA receptors govern PV neuron feature selectivity

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-08027-2 Calcium-permeable AMPA receptors are identified to have a role in maintaining low feature selectivity in a specific population of inhibitory interneurons, and this function is conserved across ferrets, rode … | Continue reading


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LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-08012-9 Cryo-electron microscopy structures of the human lysosomal transmembrane protein LYCHOS show that it comprises a transporter-like domain fused to a G-protein-coupled receptor, and that the transporter domai … | Continue reading


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Connectomic reconstruction predicts visual features used for navigation

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07967-z Electron-microscopy data are used to reconstruct the neurons that make up the anterior visual pathway in the Drosophila brain, providing insight into how visual features are encoded to guide navigation. | Continue reading


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Neuronal parts list and wiring diagram for a visual system

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07981-1 An analysis of the Drosophila connectome yields all cell types intrinsic to the optic lobe, and their rules of connectivity. | Continue reading


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Highly dynamic gamma-ray emissions are common in tropical thunderclouds

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07936-6 Tropical thunderclouds over ocean and coastal regions are shown to emit gamma rays for several hours over areas of up to a few thousand square kilometres, contradicting the quasi-stationary picture of glows … | Continue reading


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Tuft cells act as regenerative stem cells in the human intestine

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07952-6 Four distinct tuft cell states are identified by combining analysis of primary human intestinal resection material and organoids, and studying tuft cell development shows that they represent a damage-induce … | Continue reading


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RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07969-x Chromatin-associated retrotransposon RNA 5-methylcytosine can be recognized by the methyl-CpG-binding-domain protein MBD6, which guides deubiquitination of nearby monoubiquitinated Lys119 of histone H2A to … | Continue reading


@nature.com | 1 month ago

Whole-brain annotation and multi-connectome cell typing of Drosophila

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07686-5 A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics. | Continue reading


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Mortality caused by tropical cyclones in the United States

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07945-5 A large-scale evaluation of the long-term effects of tropical cyclones on human mortality in the contiguous United States estimates that the average tropical cyclone results in 7,000–11,000 excess deaths, f … | Continue reading


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Signature of the western boundary currents in local climate variability

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-08019-2 Analyses based on high-spatial-resolution data demonstrate that sea surface temperature variability in the western boundary currents has a more robust signature in local climate variability than previously … | Continue reading


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A Drosophila computational brain model reveals sensorimotor processing

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07763-9 We create a computational model of the adult Drosophila brain that accurately describes circuit responses upon activation of different gustatory and mechanosensory subtypes and generates experimentally test … | Continue reading


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Differences in misinformation sharing can lead to politically asymmetric sanctions

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07942-8 We find that conservatives tend to share more low-quality news through social media than liberals, and so even if technology companies enact politically neutral anti-misinformation policies, political asymm … | Continue reading


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Flickering gamma-ray flashes, the missing link between gamma glows and TGFs

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07893-0 Flickering gamma-ray flashes associated with terrestrial thunderstorms have been observed, which may be the missing link between gamma-ray glows and TGFs. | Continue reading


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Rapid homologue juxtaposition during meiotic chromosome pairing

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07999-5 Homologue juxtaposition during meiosis is examined in real time by imaging of tagged chromosomal loci at high resolution in budding yeast, showing that corresponding loci come together and complete pairing … | Continue reading


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Neuronal wiring diagram of an adult brain

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07558-y FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to … | Continue reading


@nature.com | 1 month ago

Network statistics of the whole-brain connectome of Drosophila

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07968-y The network of the fly brain is highly recurrent and displays rich-club organization, with a large population (30%) of preferentially connected neurons. | Continue reading


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Bulk high-temperature superconductivity in pressurized tetragonal La2PrNi2O7

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07996-8 Bulk high-temperature superconductivity observed in pressurized tetragonal La2PrNi2O7 was testified by detecting clear diamagnetic signals below about 75 K with appreciable superconducting shielding volume … | Continue reading


@nature.com | 1 month ago

The fly connectome reveals a path to the effectome

Nature, Published online: 02 October 2024; doi:10.1038/s41586-024-07982-0 Analysis of the whole-brain fly connectome reveals high-dimensional dynamics supported by many small independent circuits, motivating a proposal for optogenetic perturbation to efficiently learn a whole-bra … | Continue reading


@nature.com | 1 month ago

CRISPR helps brain stem cells regain youth in mice

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03177-9 Disabling a gene involved in metabolism rejuvenates cells’ ability to spin off new neurons. | Continue reading


@nature.com | 1 month ago

Can flashing lights stall Alzheimer’s? What the science shows

Nature, Published online: 02 October 2024; doi:10.1038/d41586-024-03147-1 Pulses of light and sound seem to have beneficial effects. But some argue it is too soon to market experimental devices. | Continue reading


@nature.com | 1 month ago

Daily briefing: Claims of fraud plague one of the most-cited neuroscience researchers

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03216-5 One of the most-cited researchers in neuroscience is facing claims his work is riddled with fraudulent data. Plus, a river merger might have given Mount Everest a height boost. | Continue reading


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What harmful microbes are lurking in the world’s 7 billion tonnes of plastic waste?

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03150-6 Pathogenic viruses and antibiotic-resistant bacteria thrive on plastic. The biohazard risks of this ‘plastisphere’ shouldn’t be overlooked in efforts to tackle the pollution crisis. | Continue reading


@nature.com | 1 month ago

‘In awe’: scientists impressed by latest ChatGPT model o1

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03169-9 The chatbot excels at science, beating PhDs on a hard science test. But it might ‘hallucinate’ more than its predecessors. | Continue reading


@nature.com | 1 month ago

Support the Pact for the Future

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03183-x The final text from the UN Summit of the Future offers a glimmer of hope for a world beset by multiple crises. | Continue reading


@nature.com | 1 month ago

The huge toll of PhDs on mental health: data reveal stark effects

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03136-4 PhD students in Sweden accessed mental-health services at increasing rates as their studies went on. | Continue reading


@nature.com | 1 month ago

Why Mount Everest is the world’s tallest mountain

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03164-0 Model suggests a massive uplift partly explains the peak’s impressive height. | Continue reading


@nature.com | 1 month ago

Peer review by committee? New journal rethinks old model

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03039-4 Teams of up to seven researchers are reviewing papers submitted to the Stacks Journal, which wants to bring evaluation of scientific work back from the brink. | Continue reading


@nature.com | 1 month ago

Deadly Marburg virus: scientists race to test vaccines in outbreak

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03218-3 There are no approved treatments for the Ebola-like haemorrhagic fever, which is spreading in Rwanda. | Continue reading


@nature.com | 1 month ago

AI to the rescue: how to enhance disaster early warnings with tech tools

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03149-z Artificial intelligence can help to reduce the impacts of natural hazards, but robust international standards are needed to ensure best practice. | Continue reading


@nature.com | 1 month ago

Why the timing of climate assessments matters

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03156-0 The Intergovernmental Panel on Climate Change and the Paris agreement must align their schedules — or progress will slip. | Continue reading


@nature.com | 1 month ago

Funders launch online resource to help researchers navigate narrative CVs

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03113-x The format allows grant applicants to showcase wider achievements, but many are unsure what to include. | Continue reading


@nature.com | 1 month ago

Jordan’s green-energy vision requires refinement

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03198-4 Jordan’s green-energy vision requires refinement | Continue reading


@nature.com | 1 month ago

International action is needed now to save the Pantanal

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03197-5 International action is needed now to save the Pantanal | Continue reading


@nature.com | 1 month ago

How walkable is your city? Online tool shows how major centres measure up

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03145-3 A platform for visualizing the accessibility of urban areas reveals striking inequalities in and between the world’s cities. | Continue reading


@nature.com | 1 month ago

Baby sea turtles ‘swim’ up from buried nests to the open air

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03142-6 Turtle hatchlings, which can begin life up to a metre deep in sand, point their heads towards the surface and make their way out onto the beach. | Continue reading


@nature.com | 1 month ago

US election has profound implications for science in Ukraine

Nature, Published online: 01 October 2024; doi:10.1038/d41586-024-03199-3 US election has profound implications for science in Ukraine | Continue reading


@nature.com | 1 month ago