The inactivation of tumour suppressor genes at the level of mRNA occurs by the generation of truncated proteins in leukaemia. | Continue reading
Here, the authors present a fully automatic computational approach for reconstructing and virtually unfolding volumetric scans of locked letters with complex internal folding, producing legible images of the letter’s contents and crease pattern while preserving letterlocking evid … | Continue reading
How robots made from soft materials can withstand high pressures. | Continue reading
Laser generates quantum randomness at a rate of 250 trillion bits per second, and could lead to devices small enough to fit on a single chip. | Continue reading
Scientists are monitoring pets, livestock and wildlife to work out where SARS-CoV-2 could hide, and whether it could resurge. | Continue reading
Fungi may have evolved up to 2.4 billion years ago, but it is unclear when they first colonized land. Here Gan and colleagues report filamentous Ediacaran microfossils from South China that may represent early terrestrial fungi. | Continue reading
Tempted to try your hand at a new technique? These tools will help you on your way. | Continue reading
Just 1% of scientists capture more than one-fifth of all citations globally — and the inequality is growing. | Continue reading
Susannah Cahalan’s investigation of the social-psychology experiment that saw healthy people sent to mental hospitals finds inconsistencies. | Continue reading
Understanding a complex microbial ecosystem such as the human gut microbiome requires information about both microbial species and the metabolites they produce and secrete. Here, the authors propose an ecology-based computational method to predict hundreds of new experimentally u … | Continue reading
No male contraceptive pills are currently available. Here, the authors use triptonide, a compound derived from a Chinese plant, to deform sperm so that they cannot move properly, thereby causing reversible infertility in male mice and monkeys. | Continue reading
Open repository will give free access to more than 160 million data points with details about individual infections. | Continue reading
Uneven transmission of the SARS-CoV-2 coronavirus has had tragic consequences — but also offers clues for how best to target control measures. | Continue reading
A giant data store quietly being built in India could free vast swathes of science for computer analysis —but is it legal? | Continue reading
Hair-raising sixteenth-century reports emphasize the tests’ control arms and societal benefit. | Continue reading
Many physicists believe that entanglement is the essence of quantum weirdness — and some now suspect that it may also be the essence of space-time geometry. | Continue reading
Myeloid cells are able to utilize a variety of monosaccharides from our diet, including fructose. Here the authors show that when monocytes are reliant on fructose as a carbon energy source they are reprogrammed towards oxidative metabolism, glutamine anaplerosis and a pro-inflam … | Continue reading
Nuclear fusion experiments with deuterium and tritium at the Joint European Torus are a crucial dress rehearsal for the mega-experiment. | Continue reading
Previously only humans and the great apes have been shown to use probabilities to make predictions about uncertain events, and integrate social and physical information into their predictions. Here, the authors demonstrate these capacities in a parrot species, the kea. | Continue reading
Analysis of three astronomical surveys provides some of the best evidence yet against the existence of a giant planet at the fringes of the Solar System. | Continue reading
Canines seem to detect coronavirus infections with remarkable accuracy, but researchers say large-scale studies are needed before the approach is scaled up. | Continue reading
Advice to the Biden administration as it seeks to account for mounting losses from storms, wildfires and other climate impacts. | Continue reading
This Review discusses strategies for the genetic engineering of adoptive T cell immunotherapies with a focus on approaches harnessing transgenic T cell receptors or chimeric antigen receptors to treat cancer. The authors also discuss the more complex levels of genetic regulation … | Continue reading
Researchers in Japan are enlisting an army of citizens to explore how storms on Earth create extreme bursts of radiation. | Continue reading
A Nature survey shows many scientists expect the virus that causes COVID-19 to become endemic, but it could pose less danger over time. | Continue reading
Human mobility plays a central role in the spread of infectious diseases and can help in forecasting incidence. Here the authors show a comparison of multiple mobility benchmarks in forecasting influenza, and demonstrate the value of a machine-learned mobility map with global cov … | Continue reading
α-Synuclein is a presynaptic protein whose aberrant aggregation is associated with Parkinson’s disease. Here, the authors show how αSynuclein-induced docking of synaptic vesicles is modulated by the lipid composition changes typically observed in neurodegeneration using an in vit … | Continue reading
Imaging of low-mass exoplanets can be achieved once the thermal background in the mid-infrared (MIR) wavelengths can be mitigated. Here, the authors present a ground-based MIR observing approach enabling imaging low-mass temperate exoplanets around nearby stars. | Continue reading
Analyses suggest that China has successfully curbed production of an ozone-depleting chemical, a win for the international treaty that protects the ozone layer. | Continue reading
The month’s sharpest science shots, selected by Nature’s photo team. | Continue reading
NINJ1 protein mediates rupture of the plasma membrane in dying cells. | Continue reading
UAE’s Hope spacecraft is poised to make pioneering measurements of the Martian atmosphere. | Continue reading
Input–output models can predict multiregional brain network dynamics in response to temporally varying patterns of ongoing direct electrical stimulation, with variabilities in prediction accuracy explained by at-rest functional connectivity. | Continue reading
Scopus has stopped adding content from most of the flagged titles, but the analysis highlights how poor-quality science is infiltrating literature. | Continue reading
Human sera from recipients of the BNT162b2 vaccine can neutralize SARS-CoV-2 viruses containing spike mutations present in globally circulating variants of concern. | Continue reading
In her latest book, Elizabeth Kolbert asks: could some environmental fixes be worse than the problems? | Continue reading
Elena Rodriguez-Falcon is breaking the mould with a hands-on institution designed to meet Britain’s growing demand for engineering graduates. | Continue reading