Brazilian fossils reveal homoplasy in the oldest mammalian jaw joint

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07971-3 The dentary–squamosal contact, traditionally considered to be a typical mammalian feature, evolved more than once and is more evolutionary labile than previously considered. | Continue reading


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Microbial iron limitation in the ocean’s twilight zone

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07905-z The distribution and uptake of siderophores across a meridional section of the eastern Pacific Ocean suggests that iron availability limits microbial metabolism in the upper mesopelagic in several large o … | Continue reading


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AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07992-y The tRNA synthases AARS1 and AARS2 are identified as evolutionarily conserved sensors of intracellular l-lactate to mediate the global lysine lactylome. | Continue reading


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Jet stream controls on European climate and agriculture since 1300 ce

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07985-x Tree-ring records used to reconstruct the variability of the European jet stream from 1300 to 2004 ce show modulation of extreme regional climate events and extensive impacts on agriculture and human well … | Continue reading


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Human hippocampal and entorhinal neurons encode the temporal structure of experience

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07973-1 Single-neuron recordings from intracranial electrodes inserted into human brains for clinical reasons suggest that the temporal structure of human experience is encoded in human hippocampal and entorhinal … | Continue reading


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Larger and more instructable language models become less reliable

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07930-y Scaling up and shaping up large language models increased their tendency to provide sensible yet incorrect answers at difficulty levels humans cannot supervise, highlighting the need for a fundamental shi … | Continue reading


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The genetic architecture of protein stability

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07966-0 By experimentally sampling from sequence spaces larger than 1010 and using thermodynamic models, the genetic structure of at least some proteins can be well described, indicating that protein genetics is … | Continue reading


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Transferrin receptor targeting chimeras for membrane protein degradation

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07947-3 Transferrin receptor targeting chimeras have been developed that enable targeting of drug resistance in epidermal growth factor receptor-driven lung cancer and reversible control of human primary chimeric … | Continue reading


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Intragenic DNA inversions expand bacterial coding capacity

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07970-4 Reversible DNA inversions found entirely within genes enable increased coding capacity by encoding multiple versions of a protein in bacteria and archaea. | Continue reading


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On human-in-the-loop optimization of human–robot interaction

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07697-2 A new approach to designing robotic systems that interact closely with people, called human-in-the-loop optimization, can improve human–robot interaction, but many important research questions remain befo … | Continue reading


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Future increase in extreme El Niño supported by past glacial changes

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07984-y A combination of palaeoclimate proxies and simulations shows that a common mechanism controls El Niño variation in cold and warm states, which supports expectations of more extreme El Niño occurrence in t … | Continue reading


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Forest fire size amplifies postfire land surface warming

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07918-8 Climate warming has increased forest fire sizes, amplifying postfire summer warming, with broadleaf trees mitigating this effect; climate-smart forestry should increase broadleaf tree cover to manage futu … | Continue reading


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The evolution of private reputations in information-abundant landscapes

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07977-x In an information-abundant landscape, people can accurately judge the reputations of others by researching only a fraction of the available information while forgiving some instances of bad behaviour. | Continue reading


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Pain: recognizing the power of non-pharmaceutical interventions

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03002-3 Physicians need alternatives to opioid drugs. Could manipulating the microbiome or virtual-reality experiences have a role in easing pain? | Continue reading


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Children with Down’s syndrome are more likely to get leukaemia: stem-cells hint at why

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03161-3 Restructuring of genome sections creates conditions that increase blood cancer risk — plus, the latest from the Nature Briefing. | Continue reading


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A dwarf planet has dirty depths, model suggests

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03088-9 Analysis finds that the mini-world Ceres hosts a frozen ocean that is progressively filled with impurities farther from the surface. | Continue reading


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Bronze Age clash was Europe’s oldest known interregional battle

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03090-1 Artefacts found in modern-day Germany suggest that northern and southern peoples clashed in the Tollense Valley millennia ago. | Continue reading


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Author Correction: An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-08057-w Author Correction: An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption | Continue reading


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H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-08063-y H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows | Continue reading


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Author Correction: High-performance 4-nm-resolution X-ray tomography using burst ptychography

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-08093-6 Author Correction: High-performance 4-nm-resolution X-ray tomography using burst ptychography | Continue reading


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Author Correction: Immune system adaptation during gender-affirming testosterone treatment

Nature, Published online: 24 September 2024; doi:10.1038/s41586-024-08081-w Author Correction: Immune system adaptation during gender-affirming testosterone treatment | Continue reading


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We must train specialists in botany and zoology — or risk more devastating extinctions

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03072-3 Failure to fund education in taxonomy could derail efforts to support conservation in low- and middle-income countries. | Continue reading


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Seven work–life balance tips from a part-time PhD student

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-02693-y Simone Willis studied part-time alongside multiple paid roles. Here’s how she managed her time, met deadlines and protected her mental health. | Continue reading


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The global H5N1 influenza panzootic in mammals

Nature, Published online: 24 September 2024; doi:10.1038/s41586-024-08054-z The global H5N1 influenza panzootic in mammals | Continue reading


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The human heart shows signs of ageing after just a month in space

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03105-x Researchers sent engineered heart tissue to the International Space Station and measured how it faired. | Continue reading


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How to stop a looming ‘splinternet’

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03110-0 Online safety is crucial, but so are privacy and decentralization. Computer scientists who set the Internet’s technical standards should be included in governance talks. | Continue reading


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Mathematics helped Britain to get in touch with continental Europe a century ago

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-02810-x An undersea cable promises to improve Britain’s relationship with Europe, and a poet’s attempt at ornithology is debunked, in Nature’s weekly step back in time. | Continue reading


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The youngest among us fight COVID-19 in their own way

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03091-0 Children under the age of five infected with SARS-CoV-2 produce lower levels of some immune cells than older children and adults do. | Continue reading


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Yo-yo dieting accelerates cardiovascular disease by reprogramming the immune system

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03030-z Can cycles of dieting increase your risk of heart attack? In mice, an alternating high-fat and low-fat diet promotes plaque build-up in arteries by modulating the body’s innate immune responses. | Continue reading


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What is a cell type, really? The quest to categorize life’s myriad forms

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03073-2 Scientists have more information than ever on how cells differ — but they still resist easy grouping. | Continue reading


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We can’t recreate ancient wilderness environments — but that’s not the point

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03122-w We can’t recreate ancient wilderness environments — but that’s not the point | Continue reading


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Gender inequity persists among journal chief editors

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03121-x Gender inequity persists among journal chief editors | Continue reading


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Floating homes need social and political acceptance in the Western world

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03119-5 Floating homes need social and political acceptance in the Western world | Continue reading


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More measures needed to ease funding competition in China

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-03120-y More measures needed to ease funding competition in China | Continue reading


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Gaza: Why is it so hard to establish the death toll?

Nature, Published online: 24 September 2024; doi:10.1038/d41586-024-02508-0 Body counts are a crude measure of the war’s impact and more reliable estimates will take time to compile. | Continue reading


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In Asia, alternative proteins are the new clean energy

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03077-y As climate and food-security pressures intensify, the world’s most populous continent sees clear opportunities to reimagine meat — just as it did for affordable solar panels. | Continue reading


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Scientists successfully ‘nuke asteroid’ — in a lab mock-up

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03128-4 Experiment shows that, in a worst-case scenario, humanity could use a nuclear explosion to save the planet from a deadly impact. | Continue reading


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Budget cuts hit world's largest cancer-research funder: what it means for scientists

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-02978-2 The US National Cancer Institute is prioritizing young investigators as it navigates its first funding decline in nearly a decade. | Continue reading


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Oldest and coldest: JWST claims a first for exoplanet imaging

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-02804-9 JWST has opened a window on exoplanet imaging by observing the planet ε Indi Ab directly. The planet’s existence had been inferred, but its age and temperature made the discovery difficult to confirm — un … | Continue reading


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‘Substandard and unworthy’: why it’s time to banish bad-mannered reviews

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-02943-z The publisher of Physics World and other journals is marking Peer Review Week 2024 by calling for more courtesy in the process. | Continue reading


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Promises and challenges of crop translational genomics

Nature, Published online: 23 September 2024; doi:10.1038/s41586-024-07713-5 This Perspective reviews crop translational genomics and how it is helping to bring laboratory genetics to the crop field. | Continue reading


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Author Correction: Birth of protein folds and functions in the virome

Nature, Published online: 23 September 2024; doi:10.1038/s41586-024-08068-7 Author Correction: Birth of protein folds and functions in the virome | Continue reading


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Octopuses and fish caught on camera hunting as a team

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03127-5 Although typically viewed as solitary animals, octopuses sometimes work with fish to entrap prey. | Continue reading


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Einstein in Oxford: the untold story of an unlikely friendship

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03075-0 Albert Einstein’s sojourns in the English city, as Nazism rose in Germany, were built on the back of a connection with a now largely forgotten don. | Continue reading


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I scale these vast trees to gather data on the effects of climate change

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03080-3 Rebecca Hsu works as a forest ecologist for the Taiwan Forestry Institute in Taipei. | Continue reading


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Daily briefing: Mathematicians have described a new class of shape: soft cells

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03131-9 Straightforward solutions to antimicrobial resistance could avert millions of deaths. Plus, Three Mile Island nuclear plant will be restarted to power Microsoft data centres | Continue reading


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Can AI feel distress? Inside a new framework to assess sentience

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03076-z From artificial-intelligence algorithms to zebrafish, this book take a precautionary approach to assessing how sentient such entities are. | Continue reading


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Why cannibal queens make a meal of fungus-ridden larvae

Nature, Published online: 23 September 2024; doi:10.1038/d41586-024-03092-z Ant larvae infected with a pathogenic fungus had better watch out for Mum. | Continue reading


@nature.com | 1 month ago