A landmark in drug discovery based on complex natural product synthesis

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@nature.com | 5 years ago

Publish houses of brick, not mansions of straw (2017)

Papers need to include fewer claims and more proof to make the scientific literature more reliable, warns William G. Kaelin Jr. | Continue reading


@nature.com | 5 years ago

When English is not your mother tongue

Seven researchers discuss the challenges posed by science’s embrace of one global language. | Continue reading


@nature.com | 5 years ago

The Wisdom of Polarized Crowds

This article explores the effect of ideological polarization on team performance. By analysing millions of edits to Wikipedia, the authors reveal that politically diverse editor teams produce higher-quality articles than homogeneous or moderate teams, and they identify the mechan … | Continue reading


@nature.com | 5 years ago

Persistent cloud cover over mega-cities linked to surface heat release

Compared to nearby rural areas, mega-cities can produce an atmosphere that is, paradoxically, drier yet persistently more cloudy. Cities are known to create an “urban heat island”, but a multi-institution team led by Natalie Theeuwes from the University of Reading now shows that … | Continue reading


@nature.com | 5 years ago

CV of Failures (2010)

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@nature.com | 5 years ago

Word-processors are ditching equation editors in favour of LaTeX

Manufacturers are ditching equation editors in word-processing software in favour of the LaTeX typesetting language. Here’s how to get started. | Continue reading


@nature.com | 5 years ago

Rechargeable-hybrid-seawater fuel cell (2014)

We presented the novel concept of a hybrid-seawater fuel cell, comprising a closed-negative electrode, a NASICON solid electrolyte, and an open-seawater positive electrode. Hard carbon and a Sn-C nanocomposite were successfully applied as alternative anode materials for this hybr … | Continue reading


@nature.com | 5 years ago

A density cusp of quiescent X-ray binaries in the central parsec of the Galaxy

Observations of 12 X-ray binaries that contain black holes within the central parsec of the Galaxy suggest the existence of hundreds more, and even more isolated black holes. | Continue reading


@nature.com | 5 years ago

Bromodomain inhibition of CBP/EP300 facilitates cellular reprogramming

A chromatin-focused chemical screen identified CBP/EP300 bromodomain inhibitors as enhancers of reprogramming. These inhibitors decrease histone H3 lysine 27 acetylation, chromatin accessibility and expression of somatic-specific genes. | Continue reading


@nature.com | 5 years ago

China announces hefty fines for unauthorised collection of DNA

A new law formalizes restrictions on the collection and use of people's genetic data. | Continue reading


@nature.com | 5 years ago

Artificial intelligence is cracking long-standing puzzles in art history

Machine learning is helping experts to figure out who painted what, a modified PET scanner can produce 3D images of the whole body in seconds and the world’s most powerful superconducting magnet. | Continue reading


@nature.com | 5 years ago

Superconducting magnet breaks strength world record

Magnet generates an unprecedented 45.5-tesla field. | Continue reading


@nature.com | 5 years ago

Organization of human and macaque auditory cortex: fMRI harmonic tone response

Norman-Haignere et al. report that humans but not macaque monkeys possess cortical regions with a strong preference for harmonic tones compared to noise. This species difference may be driven by the demands of speech and music perception in humans. | Continue reading


@nature.com | 5 years ago

Atypical behaviour and connectivity in SHANK3-mutant macaques

The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human-primate model of autism spectrum disorder and Phelan–McDermid syndrome. | Continue reading


@nature.com | 5 years ago

Whole-body PET scanner produces 3D images in seconds

The modified scanner also requires less radioactive exposure, vastly broadening its applications. | Continue reading


@nature.com | 5 years ago

Ozone Mystery Laid to Rest

A new constraint on atmospheric levels of ozone. | Continue reading


@nature.com | 5 years ago

Hawk guidance system tuned for close pursuit of erratically maneuvering targets

Hunting styles and flight morphologies of aerial predators are adapted to their habitat structure and prey behaviour. Here, the authors reconstruct flight trajectories of Harris’ Hawks Parabuteo unicinctus and find that these follow a mixed guidance law that is not thrown off by … | Continue reading


@nature.com | 5 years ago

A monolithic immersion metalens for imaging solid-state quantum emitters

Photon collection from quantum emitters is difficult, and their scale requires the use of free-space optical measurement setups which prevent packaging of quantum devices. Here, the authors design and fabricate a metasurface that acts as an immersion lens to collect and collimate … | Continue reading


@nature.com | 5 years ago

‘Broken access’ publishing corrodes quality

Funders should award competitive grants directly to journals to underwrite the costs of open access, urges Adriano Aguzzi. | Continue reading


@nature.com | 5 years ago

Brazil wins legal fight over 100M-year-old fossil bounty

A French court has ordered the return of 45 dinosaur and animal fossils to Brazil, and will soon rule on the fate of a spectacular pterosaur skeleto | Continue reading


@nature.com | 5 years ago

Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy

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@nature.com | 5 years ago

High external-efficiency nanofocusing for lens-free near-field optical nanoscopy

A two-step sequential broadband nanofocusing technique offers an external efficiency of ~50% over nearly all the visible range on a fibre-coupled plasmonic nanowire probe. Its integration with a scanning tunnelling microscope realizes lens-free tip-enhanced Raman spectroscopy wit … | Continue reading


@nature.com | 5 years ago

Magnetic field morphology in interstellar clouds: velocity gradient technique

The velocity gradient technique is used to measure the magnetic field orientations and magnetization of five low-mass star-forming molecular clouds, also finding that collapsing regions constitute a small fraction of the volume in these clouds. | Continue reading


@nature.com | 5 years ago

Deep neural network vs. commercial algorithm in low-dose CT image reconstruction

Reducing the radiation dose for medical CT scans can provide a less invasive imaging method, but requires a method for reconstructing an image up to the image quality from a full-dose scan. In this article, Wang and colleagues show that the deep learning approach, combined with t … | Continue reading


@nature.com | 5 years ago

Transition metal dichalcogenide nanodisks:Hi-index dielectric Mie nanoresonators

In individual tungsten diselenide nanodisks, excitonic and anapole modes can strongly couple to form a polariton. | Continue reading


@nature.com | 5 years ago

Linear Mitochondrial Genome in Anthozoa (Cnidaria): A Case Study in Ceriantharia

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@nature.com | 5 years ago

Act Now on Crispr Babies

Another researcher has announced controversial plans to gene edit babies. The scientific community must intervene. | Continue reading


@nature.com | 5 years ago

Boosting MRI signal-to-noise ratio using magnetic metamaterials

Magnetic resonance imaging is widely used for the diagnosis of many ailments and efforts to continuously improve image resolution and decrease acquisition time are strongly sought after. The authors demonstrate that the application of specially designed metamaterials could help i … | Continue reading


@nature.com | 5 years ago

Gorgon Stare

Sharon Weinberger commends a book on how a film inspired the United States to develop technology to capture everyone’s every move. | Continue reading


@nature.com | 5 years ago

Strain-based room-temp non-volatile MoTe2 ferroelectric phase change transistor

Strain-induced phase change in MoTe2 enables reversible channel conductivity switching in a field-effect transistor geometry. | Continue reading


@nature.com | 5 years ago

World's largest plant survey reveals alarming extinction rate

Since 1900, nearly 3 species of seed-bearing plants have disappeared per year ― 500 times faster than they would naturally. | Continue reading


@nature.com | 5 years ago

Enzymatic pathway in human gut microbiome converts A to universal O type blood

Functional metagenomic screening identified a pair of enzymes from the gut bacterium Flavonifractor plautii that can efficiently convert A antigen to the H antigen of universal O type blood. | Continue reading


@nature.com | 5 years ago

Long-standing puzzle about black holes’ influence is settled

Ultra-high-resolution models of a black hole confirm a hypothesis proposed more than 40 years ago. | Continue reading


@nature.com | 5 years ago

Palaeogenomic insights into the origins of French grapevine diversity

Thousands of varieties of wine grapes have been recorded and described in historical accounts, some going back as far as the Middle Ages, but genetic relationships between ancient and modern varieties were unknown. Genomic sequencing of 28 seeds, dating back as far as the Iron Ag … | Continue reading


@nature.com | 5 years ago

Russian biologist plans more CRISPR-edited babies

The proposal follows a Chinese scientist who claimed to have created twins from edited embryos last year. | Continue reading


@nature.com | 5 years ago

Nano-Enabled Agriculture

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@nature.com | 5 years ago

Total cholesterol and all-cause mortality – a study among 13M adults

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@nature.com | 5 years ago

How to make the thinnest possible free-standing sheets of perovskite materials

Monolayers of perovskite oxides fabricated and imaged. | Continue reading


@nature.com | 5 years ago

The human body is a mosaic of different genomes

Survey finds that ‘normal’ human tissues are riddled with mutations. | Continue reading


@nature.com | 5 years ago

Planetary rotation important for ventilation processes in deep elongated lakes

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@nature.com | 5 years ago

Hydrogeological constraint on formation of Palaeoproterozoic banded Fe formation

Banded iron formations could not have formed by postdepositional oxidation, according to four million hydrogeological box model iterations that failed to reproduce secondary oxidation on reasonable timescales. | Continue reading


@nature.com | 5 years ago

The population history of northeastern Siberia since the Pleistocene

Analyses of 34 ancient genomes from northeastern Siberia, dating to between 31,000 and 600 years ago, reveal at least three major migration events in the late Pleistocene population history of the region. | Continue reading


@nature.com | 5 years ago

A cool accretion disk around the Galactic Centre black hole

Emission from the 1.3-millimetre hydrogen recombination line reveals a rotating disk of cool gas 0.004 parsecs in radius around the supermassive black hole at the centre of our Galaxy. | Continue reading


@nature.com | 5 years ago

Palaeoproteomics Resolves Sloth Relationships

Palaeoproteomics offers an opportunity to resolve molecular phylogenies especially in contexts where ancient DNA does not preserve. Here collagen sequences resolve sloth phylogenies differently from morphology-based estimates, illuminating the utility of proteomics in systematics … | Continue reading


@nature.com | 5 years ago

Selective triplet exciton formation in a single molecule

Recombination of excitons to produce molecular light emission is made more efficient by controlling electron spin within the molecule to produce spin-triplet excitons only, without the usual accompanying spin-singlet excitons. | Continue reading


@nature.com | 5 years ago

Role of major erosion events in Earth’s dynamics

An explanation for the advent and evolution of plate tectonics on Earth. | Continue reading


@nature.com | 5 years ago

Magnetism in cold subducting slabs at mantle transition zone depths

Synchrotron Mössbauer source spectroscopy is used to reveal that haematite remains magnetic in cold subducting slabs at the depth of the transition zone in the Earth’s mantle, with implications for the locations of magnetic poles during inversions of the Earth’s magnetic field. | Continue reading


@nature.com | 5 years ago