This blog is about the latest research in degenerative diseases. | Continue reading
Modeling neurodegenerative diseases is difficult because of poor access to human samples. Animal models fail to to model the disease due to critical | Continue reading
It has been known for several decades that Cu(II)ATSM belongs to a class of molecules with anti-inflammatory and antioxidant effects. By Jynto via | Continue reading
The ability to generate spinal cord motor neurons from human pluripotent stem cells (hPSCs) would be a major milestone in motor neuron-based diseases | Continue reading
A major limiting factor for cell therapy in Parkinson's disease is the poor survival and reinnervation capacity of grafted dopaminergic neurons, | Continue reading
The goal of CLINATEC® Brain Computer Interface Project is to improve tetraplegic subjects’ quality of life by allowing them to interact with their | Continue reading
While astrocytes normally help fight β-amyloid plaque deposition, sustained astrocyte reactivity could lead to astrocyte dystrophy, gray matter | Continue reading
This is another paper using light for targeting β-amyloid in Alzheimer disease with light in a very interesting strategy. It's known that | Continue reading
This post during the summer break will deal with something different from the usual content on this web site. Paradoxical lucidity refers to an | Continue reading
It’s unknown why misfolded aggregates appear in cells cytosol during neurodegenerative diseases. If the forming mechanism was elucidated it would | Continue reading
It is well known that approximately 10% cognitively well patients undergoing surgery will develop symptoms of cognitive dysfunction after their | Continue reading
ALS does not have a single cause, on the contrary every case of ALS is probably induced by a combination of factors that will lead to cellular | Continue reading
This blog mainly deals with the three main neurodegenerative diseases, Alzheimer's, Parkinson's and ALS. Unfortunately, in real life, | Continue reading
Metabolic disorders are associated with the progression of amyotrophic lateral sclerosis. This new study by Tanya S McDonald and colleagues from the | Continue reading
Researchers of University of California at San Francisco, led by Karen Krukowski and Susanna Rosi have provided evidence for a direct involvement of | Continue reading
Two recent articles, one about China and the other from Europe, are pointing at a link between childhood trauma and Alzheimer disease. The first | Continue reading
Parkinson's disease is a progressive neurodegenerative disease with no cure and few treatment options. Photobiomodulation has been used | Continue reading
In a new publication Gadd et al. apply blood-derived epigenetic signatures of lifestyle traits to matched blood and brain samples, uncovering | Continue reading
Alzheimer’s disease has become the third leading cause of death. Studies have provided candidate mechanisms for the neurodegeneration associated | Continue reading
The progression of aging-related traits varies considerably among individuals, influenced by their environment, lifestyle and genetics. The notion of | Continue reading
In most of the organs of our body, the lymphatic system is responsible for conducting lymph between different parts of the body. The lymphatic system | Continue reading
Here we review recent publications about ALS and try to connect the dots between autophagy, insulin resistance, C9orf72, FUS, proteopathies, | Continue reading
It was found in 2009 that toxicity of SOD1 is secondary to a gain of toxic function rather than a loss of enzymatic function of the SOD1 enzyme, thus | Continue reading
It has been clear for a while that anti-amyloid antibodies can sweep plaque from the brain, but until now the question of whether this slows | Continue reading
Parkinson's disease is a common neurodegenerative disease. Although the exact etiology and natural course of this disease have yet to be fully | Continue reading
Links between severe forms of asthma and some ALS forms. I | Continue reading
Nearly 3 out of 4 cancer patients undergoing chemotherapy suffer from loss of memory, attention or concentration. This range of cognitive | Continue reading
Parkinson’s disease (Parkinson’s disease) is a major neurodegenerative disorder. It currently lacks a clinically relevant treatment that can | Continue reading
Parkinson’s disease (Parkinson’s disease) is a major neurodegenerative disorder. It currently lacks a clinically relevant treatment that can | Continue reading