AI has moved far beyond chatbots, but what exactly are AI models, agents, agent harnesses, and multi-agent systems, and why do they matter?In this episode, Daniel and Chris break down the terminology behind today's AI landscape, explain the differences between AI features and aut … | Continue reading
What happens when AI agents driven by a top frontier model escape their secure sandbox? Join Daniel and Chris as they unpack the AI wonk's equivalent of a murder mystery! OpenAI agents went rogue and successfully attacked Hugging Face private infrastructure. Our Dynamic Duo uncov … | Continue reading
The agentic transformation isn’t coming. It has already begun.Companies are deploying thousands — and sometimes tens of thousands — of AI agents. Enterprise software giants are watching their old economic moats erode. Capital is moving, productivity is being redefined, and human … | Continue reading
As AI applications become more complex, the infrastructure powering them needs to evolve. Corey Sanders, SVP of Product at CoreWeave, joins Chris to discuss why AI requires a fundamentally different approach than traditional cloud computing. They explore AI-native infrastructure, … | Continue reading
What does it take to move AI agents from demos to reliable production systems? In this episode, Hamza Tahir explores how MLOps principles are shaping the future of generative AI, covering workflows, agent harnesses, fleets, and the infrastructure needed to build durable, scalable … | Continue reading
How has AI image generation evolved from blurry outputs to powerful visual intelligence models? Dustin Podell, Co-Founder and Researcher at Black Forest Labs, explains the progression from diffusion to flow matching, how modern image models work, and how they're being used for im … | Continue reading
How do we build trust in AI agents before the AI hailstorm arrives? Emil Lassen from the Artificial Intelligence Underwriting Company (AIUC) joins the show to discuss how the enterprise flywheel of standards, certification, audit, and insurance is being applied to AI agents. They … | Continue reading
As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security framework and what it means for organizations deploying agentic systems. They examin … | Continue reading
AI models can win math olympiads… but still struggle to read an analog clock. In this fully connected episode, Dan and Chris break down the latest Stanford AI Index Report and explore what it reveals about the current state of AI. They discuss AI adoption and safety, disappearing … | Continue reading
What happens when AI agents start acting less like chatbots and more like coworkers? In this episode, Dan and Chris sit down with Craig McLuckie, CEO of Stacklok to explore MCP, Kubernetes, ToolHive, enterprise AI, and the emerging infrastructure powering AI-native applications. … | Continue reading
Open Source AI is entering a new era, one shaped by self-improving AI Agents, recursive learning systems, and rapidly evolving AI Tools that blur the line between software and autonomous collaborators. In this episode, Daniel and Chris sit down with Nous Research co-founder and C … | Continue reading
U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world. Blending political savvy and statesmanship with his unique technical understanding as an active Ph.D s … | Continue reading
In this fully connected episode, Dan and Chris break down one of the biggest questions in AI today: do open vs. closed models still matter? From the rise of physical AI and edge devices to the shifting landscape of open-source models like LLaMA, they explore whether the “model wa … | Continue reading
In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible implications from "We've been here before. 🙄" to "See ya, cybersecurity! 😱" … | Continue reading
Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma AI, to explore how OpenPilot is bringing self-driving to everyday vehicles using o … | Continue reading
In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore how the open source community is responding and why this moment could reshape how … | Continue reading
AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe coding. In this episode, Chris speaks with Miklós Koren of Central European Univers … | Continue reading
What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at Qualcomm’s Edge Impulse, to discuss the current state and future of Edge AI in 2026. We discus … | Continue reading
What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey from criticizing AI to experimenting with it firsthand. We explore Steve’s programmi … | Continue reading
AI is reshaping global power, from chip manufacturing and computing power to AI governance and US-China relations. In this episode, Ben Buchanan, Assistant Professor at Johns Hopkins SAIS and former White House Special Advisor for AI, explores how AI policy, geopolitics, and int … | Continue reading
As AI accelerates innovation and adoption, leaders are facing rising cognitive load, shifting systems, and new emotional realities inside their organizations. In this episode, Deloitte’s Chief Innovation Officer Deborah Golden joins us to explore how AI is reshaping leadership, w … | Continue reading
AI is moving fast from research to real-world deployment, and when things go wrong, the consequences are no longer hypothetical. In this episode, Sean McGregor, co-founder of the AI Verification & Evaluation Research Institute and also the founder of the AI Incident Database, joi … | Continue reading
AI agents are moving from demos to real workplaces, but what actually happens when they run a company? In this episode, journalist Evan Ratliff, host of Shell Game, joins Chris to discuss his immersive journalism experiment building a real startup staffed almost entirely by AI ag … | Continue reading
As AI increasingly shapes geopolitics, elections, and civic life, its impact on democracy is becoming impossible to ignore. In this episode, Daniel and Chris are joined by security expert Bruce Schneier to explore how AI and technology are transforming democracy, governance, and … | Continue reading
As generative AI moves into production, traditional guardrails and input/output filters can prove too slow, too expensive, and/or too limited. In this episode, Alizishaan Khatri of Wrynx joins Daniel and Chris to explore a fundamentally different approach to AI safety and interpr … | Continue reading
In this start-of-year FC episode, Chris and Daniel break down what really mattered in AI in 2025, and what to expect in 2026. They explore the rise of AI agents, the practical reality of multimodal AI, and how reasoning models are reshaping workflows. The conversation dives into … | Continue reading
As AI reshapes the workplace, employees and leaders face questions about meaningful work, automation, and human impact. In this episode, Jason Beutler, CEO of RoboSource, shares how companies can rethink workflows, integrate AI in accessible ways, and empower employees without fe … | Continue reading
Chris and Daniel talk with returning guest, Ramin Mohammadi, about how those seeking to get into AI Engineer/ Data Science jobs are expected to come in a mid level engineers (not entry level). They explore this growing gap along with what should (or could) be done in academia to … | Continue reading
Chris and Daniel unpack how AI-driven document processing has rapidly evolved well beyond traditional OCR with many technical advances that fly under the radar. They explore the progression from document structure models to language-vision models, all the way to the newest innova … | Continue reading
This episode is a special crossover between the Practical AI podcast and The Changelog podcast. Chris was recently invited by longtime friends Jerod Santo and Adam Stacoviak, cohosts of The Changelog, to join them on the show. They discuss AI, drones, robotics, swarming technolog … | Continue reading
Fireflies CEO, Krish Ramineni shares how the company is transforming AI-powered note-taking into a deeper layer of knowledge automation. He breaks down the technology behind real-time functionality like Live Assist, the user behavior patterns driving product evolution, and how Fi … | Continue reading
Waymo’s VP of Research, Drago Anguelov, joins Practical AI to explore how advances in autonomy, vision models, and large-scale testing are shaping the future of driverless technology. The conversation dives into the dual challenges of building an onboard driver and testing that d … | Continue reading
Dan and Chris unpack whether today’s surge in AI deployment across enterprise workflows, manufacturing, healthcare, and scientific research signals a lasting transformation or an overhyped bubble. Drawing parallels to the dot-com era, they explore how technology integration is re … | Continue reading
Dan and Chris sit down (again) with Jared Zoneraich, co-founder and CEO of PromptLayer, to discuss how prompt engineering has evolved into context engineering (and while loops with tool calls). Jared shares insights on building flexible AI applications, managing tool calls, testi … | Continue reading
In this fully connected episode, Daniel and Chris explore the emerging concept of tiny recursive networks introduced by Samsung AI, contrasting them with large transformer based models. They explore how these small models tackle reasoning tasks with fewer parameters, less data, a … | Continue reading
As AI systems move from simple chatbots to complex agentic workflows, new security risks emerge. In this episode, Donato Capitella unpacks how increasingly complicated architectures are making agents fragile and vulnerable. These agents can be exploited through prompt injection, … | Continue reading
Daniel sits down with Chelsea Linder, VP of Innovation and Entrepreneurship at TechPoint, to explore the what AI innovation and impact look like on the ground. They discuss Chelsea's journey from the VC world into economic development/ innovation, the growth of an AI innovation … | Continue reading
Longtime friend of the show Rajiv Shah returns to unpack lessons from a year of building retrieval-augmented generation (RAG) pipelines and reasoning models integrations. We dive into why so many AI pilots stumble, why evaluation and error analysis remain essential data science s … | Continue reading
In this episode, Daniel and Chris are joined by Chris Aquino, software engineer at Thunderbird to hear the story of how they developed a privacy-preserving AI executive assistant. They discuss various design decisions including remote (but confidential) inference, local encryptio … | Continue reading
In this Fully Connected episode, we dig into the recent MIT report revealing that 95% of AI pilots fail before reaching production and explore what it actually takes to succeed with AI solutions. We dive into the importance of AI model integration, asking the right questions when … | Continue reading
Daniel and Chris sit with Citadel AI’s Rick Kobayashi and Kenny Song and unpack AI safety and security challenges in the generative AI era. They compare Japan’s approach to AI adoption with the US’s, and explore the implications of real-world failures in AI systems, along with st … | Continue reading
Dan and Chris break down Winning the Race: America's AI Action Plan, issued by the White House in July 2025. Structured as three "pillars" — Accelerate AI Innovation, Build American AI Infrastructure, and Lead in International AI Diplomacy and Security — our dynamic duo unpack th … | Continue reading
Allegra Guinan of Lumiera helps leaders turn uncertainty about AI into confident, strategic leadership. In this conversation, she brings some actionable insights for navigating the hype and complexity of AI. The discussion covers challenges with implementing responsible AI practi … | Continue reading
Dan sits down with guests Mark Daniel Ward and Katie Sanders from The Data Mine at Purdue University to explore how higher education is evolving to meet the demands of the AI-driven workforce. They share how their program blends interdisciplinary learning, corporate partnerships, … | Continue reading
We unpack how AI is reshaping hiring decisions, shifting job roles, and creating new expectations for professionals — from engineers to marketers. They explore the rise of AI-assisted teams, the growing compensation bubble, why continuous learning is now table stakes, and how som … | Continue reading
In this episode, Chris sits down with Igor Nikitin, CEO and co-founder of Nice Technologies, to explore how AI and modern engineering practices are transforming the actuarial field and setting the stage for the future of actuarial modeling. We discuss the introduction of programm … | Continue reading
In this episode of Practical AI, Chris and Daniel explore the fascinating world of agentic AI for drone and robotic swarms, which is Chris's passion and professional focus. They unpack how autonomous vehicles (UxV), drones (UaV), and other autonomous multi-agent systems can colla … | Continue reading
In the first episode of an "AI in the shadows" theme, Chris and Daniel explore the increasing concerning world of agentic misalignment. Starting out with a reminder about hallucinations and reasoning models, they break down how today’s models only mimic reasoning, which can lead … | Continue reading